Asad M - Search Results

1

A novel class of Plasmodial ClpP protease inhibitors as potential antimalarial agents.

Mundra S, Thakur V, Bello AM, Rathore S, Asad M, Wei L, Yang J, Chakka SK, Mahesh R, Malhotra P, Mohmmed A, Kotra LP. Mundra S, et al. Among authors: asad m. Bioorg Med Chem. 2017 Oct 15;25(20):5662-5677. doi: 10.1016/j.bmc.2017.08.049. Epub 2017 Sep 5. Bioorg Med Chem. 2017. PMID: 28917450

2

A cyanobacterial serine protease of Plasmodium falciparum is targeted to the apicoplast and plays an important role in its growth and development.

Rathore S, Sinha D, Asad M, Böttcher T, Afrin F, Chauhan VS, Gupta D, Sieber SA, Mohmmed A. Rathore S, et al. Among authors: asad m. Mol Microbiol. 2010 Aug;77(4):873-90. doi: 10.1111/j.1365-2958.2010.07251.x. Epub 2010 Jun 10. Mol Microbiol. 2010. PMID: 20545854 Free article.

3

Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death.

Rathore S, Jain S, Sinha D, Gupta M, Asad M, Srivastava A, Narayanan MS, Ramasamy G, Chauhan VS, Gupta D, Mohmmed A. Rathore S, et al. Among authors: asad m. Cell Death Dis. 2011 Nov 24;2(11):e231. doi: 10.1038/cddis.2011.118. Cell Death Dis. 2011. PMID: 22113196 Free PMC article.

4

Identification of a potent combination of key Plasmodium falciparum merozoite antigens that elicit strain-transcending parasite-neutralizing antibodies.

Pandey AK, Reddy KS, Sahar T, Gupta S, Singh H, Reddy EJ, Asad M, Siddiqui FA, Gupta P, Singh B, More KR, Mohmmed A, Chitnis CE, Chauhan VS, Gaur D. Pandey AK, et al. Among authors: asad m. Infect Immun. 2013 Feb;81(2):441-51. doi: 10.1128/IAI.01107-12. Epub 2012 Nov 26. Infect Immun. 2013. PMID: 23184525 Free PMC article.

5

Structural insights into the inactive subunit of the apicoplast-localized caseinolytic protease complex of Plasmodium falciparum.

El Bakkouri M, Rathore S, Calmettes C, Wernimont AK, Liu K, Sinha D, Asad M, Jung P, Hui R, Mohmmed A, Houry WA. El Bakkouri M, et al. Among authors: asad m. J Biol Chem. 2013 Jan 11;288(2):1022-31. doi: 10.1074/jbc.M112.416560. Epub 2012 Nov 28. J Biol Chem. 2013. PMID: 23192353 Free PMC article.

6

The prokaryotic ClpQ protease plays a key role in growth and development of mitochondria in Plasmodium falciparum.

Jain S, Rathore S, Asad M, Hossain ME, Sinha D, Datta G, Mohmmed A. Jain S, et al. Among authors: asad m. Cell Microbiol. 2013 Oct;15(10):1660-73. doi: 10.1111/cmi.12142. Epub 2013 Apr 11. Cell Microbiol. 2013. PMID: 23521916

7

Cloning, expression, purification and refolding of microtubule affinity-regulating kinase 4 expressed in Escherichia coli.

Naz F, Asad M, Malhotra P, Islam A, Ahmad F, Hassan MI. Naz F, et al. Among authors: asad m. Appl Biochem Biotechnol. 2014 Mar;172(6):2838-48. doi: 10.1007/s12010-014-0733-5. Epub 2014 Jan 21. Appl Biochem Biotechnol. 2014. PMID: 24446173

8

Eps15 homology domain containing protein of Plasmodium falciparum (PfEHD) associates with endocytosis and vesicular trafficking towards neutral lipid storage site.

Thakur V, Asad M, Jain S, Hossain ME, Gupta A, Kaur I, Rathore S, Ali S, Khan NJ, Mohmmed A. Thakur V, et al. Among authors: asad m. Biochim Biophys Acta. 2015 Nov;1853(11 Pt A):2856-69. doi: 10.1016/j.bbamcr.2015.08.007. Epub 2015 Aug 15. Biochim Biophys Acta. 2015. PMID: 26284889 Free article.

9

Plasmodium falciparum OTU-like cysteine protease (PfOTU) is essential for apicoplast homeostasis and associates with noncanonical role of Atg8.

Datta G, Hossain ME, Asad M, Rathore S, Mohmmed A. Datta G, et al. Among authors: asad m. Cell Microbiol. 2017 Sep;19(9). doi: 10.1111/cmi.12748. Epub 2017 May 17. Cell Microbiol. 2017. PMID: 28423214

10

Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: Artemisinin-peptidyl vinyl phosphonate hybrid molecules as new antimalarials.

Aratikatla EK, Kalamuddin M, Rana KC, Datta G, Asad M, Sundararaman S, Malhotra P, Mohmmed A, Bhattacharya AK. Aratikatla EK, et al. Among authors: asad m. Eur J Med Chem. 2021 Aug 5;220:113454. doi: 10.1016/j.ejmech.2021.113454. Epub 2021 Apr 14. Eur J Med Chem. 2021. PMID: 33901900

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