Tepper PG - Search Results

1

Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency.

Di Meo I, Colombelli C, Srinivasan B, de Villiers M, Hamada J, Jeong SY, Fox R, Woltjer RL, Tepper PG, Lahaye LL, Rizzetto E, Harrs CH, de Boer T, van der Zwaag M, Jenko B, Čusak A, Pahor J, Kosec G, Grzeschik NA, Hayflick SJ, Tiranti V, Sibon OCM. Di Meo I, et al. Among authors: tepper pg. Sci Rep. 2017 Sep 12;7(1):11260. doi: 10.1038/s41598-017-11564-8. Sci Rep. 2017. PMID: 28900161 Free PMC article.

2

Rapid chemoenzymatic route to glutamate transporter inhibitor l-TFB-TBOA and related amino acids.

Fu H, Younes SH, Saifuddin M, Tepper PG, Zhang J, Keller E, Heeres A, Szymanski W, Poelarends GJ. Fu H, et al. Among authors: tepper pg. Org Biomol Chem. 2017 Mar 21;15(11):2341-2344. doi: 10.1039/c7ob00305f. Epub 2017 Feb 28. Org Biomol Chem. 2017. PMID: 28244539

3

Cytotoxic Deoxypodophyllotoxin Can Be Extracted in High Purity from Anthriscus sylvestris Roots by Supercritical Carbon Dioxide.

Seegers CLC, Tepper PG, Setroikromo R, Quax WJ. Seegers CLC, et al. Among authors: tepper pg. Planta Med. 2018 May;84(8):544-550. doi: 10.1055/s-0043-123938. Epub 2017 Dec 18. Planta Med. 2018. PMID: 29253908

4

Modular Enzymatic Cascade Synthesis of Vitamin B₅ and Its Derivatives.

Abidin MZ, Saravanan T, Zhang J, Tepper PG, Strauss E, Poelarends GJ. Abidin MZ, et al. Among authors: tepper pg. Chemistry. 2018 Nov 27;24(66):17434-17438. doi: 10.1002/chem.201804151. Epub 2018 Oct 30. Chemistry. 2018. PMID: 30192043 Free PMC article.

5

Discovery of an Escherichia coli esterase with high activity and enantioselectivity toward 1,2-O-isopropylideneglycerol esters.

Godinho LF, Reis CR, Tepper PG, Poelarends GJ, Quax WJ. Godinho LF, et al. Among authors: tepper pg. Appl Environ Microbiol. 2011 Sep;77(17):6094-9. doi: 10.1128/AEM.05122-11. Epub 2011 Jul 15. Appl Environ Microbiol. 2011. PMID: 21764964 Free PMC article.

6

Stereochemical Control of Enzymatic Carbon-Carbon Bond-Forming Michael-Type Additions by "Substrate Engineering".

Miao Y, Tepper PG, Geertsema EM, Poelarends GJ. Miao Y, et al. Among authors: tepper pg. European J Org Chem. 2016 Nov;2016(32):5350-5354. doi: 10.1002/ejoc.201601126. Epub 2016 Oct 25. European J Org Chem. 2016. PMID: 27917069 Free PMC article.

7

Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors.

Fu H, Zhang J, Tepper PG, Bunch L, Jensen AA, Poelarends GJ. Fu H, et al. Among authors: tepper pg. J Med Chem. 2018 Sep 13;61(17):7741-7753. doi: 10.1021/acs.jmedchem.8b00700. Epub 2018 Aug 15. J Med Chem. 2018. PMID: 30011368 Free PMC article.

8

Biocatalytic enantioselective hydroaminations enabling synthesis of N-arylalkyl-substituted L-aspartic acids.

Abidin MZ, Saravanan T, Bothof L, Tepper PG, Thunnissen AWH, Poelarends GJ. Abidin MZ, et al. Among authors: tepper pg. Org Biomol Chem. 2021 Jul 28;19(29):6407-6411. doi: 10.1039/d1ob00748c. Org Biomol Chem. 2021. PMID: 34235532 Free PMC article.

9

Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.

Zhang J, Grandi E, Fu H, Saravanan T, Bothof L, Tepper PG, Thunnissen AWH, Poelarends GJ. Zhang J, et al. Among authors: tepper pg. Angew Chem Int Ed Engl. 2020 Jan 2;59(1):429-435. doi: 10.1002/anie.201910704. Epub 2019 Nov 19. Angew Chem Int Ed Engl. 2020. PMID: 31625664 Free PMC article.

10

Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes.

Geertsema EM, Miao Y, Tepper PG, de Haan P, Zandvoort E, Poelarends GJ. Geertsema EM, et al. Among authors: tepper pg. Chemistry. 2013 Oct 18;19(43):14407-10. doi: 10.1002/chem.201302351. Epub 2013 Sep 24. Chemistry. 2013. PMID: 24115023

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