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Acetyl-4'-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency.
Di Meo I, Colombelli C, Srinivasan B, de Villiers M, Hamada J, Jeong SY, Fox R, Woltjer RL, Tepper PG, Lahaye LL, Rizzetto E, Harrs CH, de Boer T, van der Zwaag M, Jenko B, Čusak A, Pahor J, Kosec G, Grzeschik NA, Hayflick SJ, Tiranti V, Sibon OCM. Di Meo I, et al. Among authors: srinivasan b. Sci Rep. 2017 Sep 12;7(1):11260. doi: 10.1038/s41598-017-11564-8. Sci Rep. 2017. PMID: 28900161 Free PMC article.
Extracellular 4'-phosphopantetheine is a source for intracellular coenzyme A synthesis.
Srinivasan B, Baratashvili M, van der Zwaag M, Kanon B, Colombelli C, Lambrechts RA, Schaap O, Nollen EA, Podgoršek A, Kosec G, Petković H, Hayflick S, Tiranti V, Reijngoud DJ, Grzeschik NA, Sibon OC. Srinivasan B, et al. Nat Chem Biol. 2015 Oct;11(10):784-92. doi: 10.1038/nchembio.1906. Epub 2015 Aug 31. Nat Chem Biol. 2015. PMID: 26322826
Pantethine rescues a Drosophila model for pantothenate kinase-associated neurodegeneration.
Rana A, Seinen E, Siudeja K, Muntendam R, Srinivasan B, van der Want JJ, Hayflick S, Reijngoud DJ, Kayser O, Sibon OC. Rana A, et al. Among authors: srinivasan b. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6988-93. doi: 10.1073/pnas.0912105107. Epub 2010 Mar 29. Proc Natl Acad Sci U S A. 2010. PMID: 20351285 Free PMC article.
Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.
Oleaga C, Bernabini C, Smith AS, Srinivasan B, Jackson M, McLamb W, Platt V, Bridges R, Cai Y, Santhanam N, Berry B, Najjar S, Akanda N, Guo X, Martin C, Ekman G, Esch MB, Langer J, Ouedraogo G, Cotovio J, Breton L, Shuler ML, Hickman JJ. Oleaga C, et al. Among authors: srinivasan b. Sci Rep. 2016 Feb 3;6:20030. doi: 10.1038/srep20030. Sci Rep. 2016. PMID: 26837601 Free PMC article.
TEER measurement techniques for in vitro barrier model systems.
Srinivasan B, Kolli AR, Esch MB, Abaci HE, Shuler ML, Hickman JJ. Srinivasan B, et al. J Lab Autom. 2015 Apr;20(2):107-26. doi: 10.1177/2211068214561025. Epub 2015 Jan 13. J Lab Autom. 2015. PMID: 25586998 Free PMC article. Review.
535 results