Ayad NG - Search Results

1

Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations.

Allen BK, Mehta S, Ember SWJ, Zhu JY, Schönbrunn E, Ayad NG, Schürer SC. Allen BK, et al. Among authors: ayad ng. ACS Omega. 2017 Aug 31;2(8):4760-4771. doi: 10.1021/acsomega.7b00553. Epub 2017 Aug 21. ACS Omega. 2017. PMID: 28884163 Free PMC article.

2

BET bromodomain proteins are required for glioblastoma cell proliferation.

Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. Pastori C, et al. Among authors: ayad ng. Epigenetics. 2014 Apr;9(4):611-20. doi: 10.4161/epi.27906. Epub 2014 Feb 19. Epigenetics. 2014. PMID: 24496381 Free PMC article.

3

Casein kinase 1δ-dependent Wee1 protein degradation.

Penas C, Ramachandran V, Simanski S, Lee C, Madoux F, Rahaim RJ, Chauhan R, Barnaby O, Schurer S, Hodder P, Steen J, Roush WR, Ayad NG. Penas C, et al. Among authors: ayad ng. J Biol Chem. 2014 Jul 4;289(27):18893-903. doi: 10.1074/jbc.M114.547661. Epub 2014 May 9. J Biol Chem. 2014. PMID: 24817118 Free PMC article.

4

Epigenetic pathways and glioblastoma treatment: insights from signaling cascades.

Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG. Allen BK, et al. Among authors: ayad ng. J Cell Biochem. 2015 Mar;116(3):351-63. doi: 10.1002/jcb.24990. J Cell Biochem. 2015. PMID: 25290986 Review.

5

Screening of cell cycle fusion proteins to identify kinase signaling networks.

Trojanowsky M, Vidovic D, Simanski S, Penas C, Schurer S, Ayad NG. Trojanowsky M, et al. Among authors: ayad ng. Cell Cycle. 2015;14(8):1274-81. doi: 10.1080/15384101.2015.1006987. Cell Cycle. 2015. PMID: 25606665 Free PMC article.

6

GSK3 inhibitors stabilize Wee1 and reduce cerebellar granule cell progenitor proliferation.

Penas C, Mishra JK, Wood SD, Schürer SC, Roush WR, Ayad NG. Penas C, et al. Among authors: ayad ng. Cell Cycle. 2015;14(3):417-24. doi: 10.4161/15384101.2014.974439. Cell Cycle. 2015. PMID: 25616418 Free PMC article.

7

Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4.

Allen BK, Mehta S, Ember SW, Schonbrunn E, Ayad N, Schürer SC. Allen BK, et al. Sci Rep. 2015 Nov 24;5:16924. doi: 10.1038/srep16924. Sci Rep. 2015. PMID: 26596901 Free PMC article.

8

Drug Repositioning in Glioblastoma: A Pathway Perspective.

Tan SK, Jermakowicz A, Mookhtiar AK, Nemeroff CB, Schürer SC, Ayad NG. Tan SK, et al. Among authors: ayad ng. Front Pharmacol. 2018 Mar 16;9:218. doi: 10.3389/fphar.2018.00218. eCollection 2018. Front Pharmacol. 2018. PMID: 29615902 Free PMC article. Review.

9

Sustainable data and metadata management at the BD2K-LINCS Data Coordination and Integration Center.

Stathias V, Koleti A, Vidović D, Cooper DJ, Jagodnik KM, Terryn R, Forlin M, Chung C, Torre D, Ayad N, Medvedovic M, Ma'ayan A, Pillai A, Schürer SC. Stathias V, et al. Sci Data. 2018 Jun 19;5:180117. doi: 10.1038/sdata.2018.117. Sci Data. 2018. PMID: 29917015 Free PMC article.

10

Drug and disease signature integration identifies synergistic combinations in glioblastoma.

Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, Sarkaria JN, Subramanian A, Golub TR, Schürer SC, Ayad NG. Stathias V, et al. Among authors: ayad ng. Nat Commun. 2018 Dec 14;9(1):5315. doi: 10.1038/s41467-018-07659-z. Nat Commun. 2018. PMID: 30552330 Free PMC article.

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