Liu DR - Search Results

1

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR. Komor AC, et al. Among authors: liu dr. Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug. Sci Adv. 2017. PMID: 28875174 Free PMC article.

2

Negative selection and stringency modulation in phage-assisted continuous evolution.

Carlson JC, Badran AH, Guggiana-Nilo DA, Liu DR. Carlson JC, et al. Among authors: liu dr. Nat Chem Biol. 2014 Mar;10(3):216-22. doi: 10.1038/nchembio.1453. Epub 2014 Feb 2. Nat Chem Biol. 2014. PMID: 24487694 Free PMC article.

3

A system for the continuous directed evolution of proteases rapidly reveals drug-resistance mutations.

Dickinson BC, Packer MS, Badran AH, Liu DR. Dickinson BC, et al. Among authors: liu dr. Nat Commun. 2014 Oct 30;5:5352. doi: 10.1038/ncomms6352. Nat Commun. 2014. PMID: 25355134 Free PMC article.

4

In vivo continuous directed evolution.

Badran AH, Liu DR. Badran AH, et al. Among authors: liu dr. Curr Opin Chem Biol. 2015 Feb;24:1-10. doi: 10.1016/j.cbpa.2014.09.040. Epub 2014 Nov 7. Curr Opin Chem Biol. 2015. PMID: 25461718 Free PMC article. Review.

5

Methods for the directed evolution of proteins.

Packer MS, Liu DR. Packer MS, et al. Among authors: liu dr. Nat Rev Genet. 2015 Jul;16(7):379-94. doi: 10.1038/nrg3927. Epub 2015 Jun 9. Nat Rev Genet. 2015. PMID: 26055155 Review.

6

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR. Hubbard BP, et al. Among authors: liu dr. Nat Methods. 2015 Oct;12(10):939-42. doi: 10.1038/nmeth.3515. Epub 2015 Aug 10. Nat Methods. 2015. PMID: 26258293 Free PMC article.

7

Development of potent in vivo mutagenesis plasmids with broad mutational spectra.

Badran AH, Liu DR. Badran AH, et al. Among authors: liu dr. Nat Commun. 2015 Oct 7;6:8425. doi: 10.1038/ncomms9425. Nat Commun. 2015. PMID: 26443021 Free PMC article.

8

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. Komor AC, et al. Among authors: liu dr. Nature. 2016 May 19;533(7603):420-4. doi: 10.1038/nature17946. Epub 2016 Apr 20. Nature. 2016. PMID: 27096365 Free PMC article.

9

Continuous evolution of Bacillus thuringiensis toxins overcomes insect resistance.

Badran AH, Guzov VM, Huai Q, Kemp MM, Vishwanath P, Kain W, Nance AM, Evdokimov A, Moshiri F, Turner KH, Wang P, Malvar T, Liu DR. Badran AH, et al. Among authors: liu dr. Nature. 2016 May 5;533(7601):58-63. doi: 10.1038/nature17938. Epub 2016 Apr 27. Nature. 2016. PMID: 27120167 Free PMC article.

10

A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells.

Chaikind B, Bessen JL, Thompson DB, Hu JH, Liu DR. Chaikind B, et al. Among authors: liu dr. Nucleic Acids Res. 2016 Nov 16;44(20):9758-9770. doi: 10.1093/nar/gkw707. Epub 2016 Aug 11. Nucleic Acids Res. 2016. PMID: 27515511 Free PMC article.

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