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Identification of HSP90 inhibitors as a novel class of senolytics.
Fuhrmann-Stroissnigg H, Ling YY, Zhao J, McGowan SJ, Zhu Y, Brooks RW, Grassi D, Gregg SQ, Stripay JL, Dorronsoro A, Corbo L, Tang P, Bukata C, Ring N, Giacca M, Li X, Tchkonia T, Kirkland JL, Niedernhofer LJ, Robbins PD. Fuhrmann-Stroissnigg H, et al. Among authors: niedernhofer lj. Nat Commun. 2017 Sep 4;8(1):422. doi: 10.1038/s41467-017-00314-z. Nat Commun. 2017. PMID: 28871086 Free PMC article.
Accelerated aging of intervertebral discs in a mouse model of progeria.
Vo N, Seo HY, Robinson A, Sowa G, Bentley D, Taylor L, Studer R, Usas A, Huard J, Alber S, Watkins SC, Lee J, Coehlo P, Wang D, Loppini M, Robbins PD, Niedernhofer LJ, Kang J. Vo N, et al. Among authors: niedernhofer lj. J Orthop Res. 2010 Dec;28(12):1600-7. doi: 10.1002/jor.21153. J Orthop Res. 2010. PMID: 20973062 Free PMC article.
Premature aging-related peripheral neuropathy in a mouse model of progeria.
Goss JR, Stolz DB, Robinson AR, Zhang M, Arbujas N, Robbins PD, Glorioso JC, Niedernhofer LJ. Goss JR, et al. Among authors: niedernhofer lj. Mech Ageing Dev. 2011 Aug;132(8-9):437-42. doi: 10.1016/j.mad.2011.04.010. Epub 2011 May 11. Mech Ageing Dev. 2011. PMID: 21596054 Free PMC article.
A mouse model of accelerated liver aging caused by a defect in DNA repair.
Gregg SQ, Gutiérrez V, Robinson AR, Woodell T, Nakao A, Ross MA, Michalopoulos GK, Rigatti L, Rothermel CE, Kamileri I, Garinis GA, Stolz DB, Niedernhofer LJ. Gregg SQ, et al. Among authors: niedernhofer lj. Hepatology. 2012 Feb;55(2):609-21. doi: 10.1002/hep.24713. Hepatology. 2012. PMID: 21953681 Free PMC article.
ISSLS prize winner: inhibition of NF-κB activity ameliorates age-associated disc degeneration in a mouse model of accelerated aging.
Nasto LA, Seo HY, Robinson AR, Tilstra JS, Clauson CL, Sowa GA, Ngo K, Dong Q, Pola E, Lee JY, Niedernhofer LJ, Kang JD, Robbins PD, Vo NV. Nasto LA, et al. Among authors: niedernhofer lj. Spine (Phila Pa 1976). 2012 Oct 1;37(21):1819-25. doi: 10.1097/BRS.0b013e31824ee8f7. Spine (Phila Pa 1976). 2012. PMID: 22343279 Free PMC article.
183 results