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Erratum: Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MWD, Duvall JR, Kihlberg J. Over B, et al. Among authors: kihlberg j. Nat Chem Biol. 2017 Jul 18;13(8):922. doi: 10.1038/nchembio0817-922a. Nat Chem Biol. 2017. PMID: 28853740 No abstract available.
Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.
Over B, McCarren P, Artursson P, Foley M, Giordanetto F, Grönberg G, Hilgendorf C, Lee MD 4th, Matsson P, Muncipinto G, Pellisson M, Perry MW, Svensson R, Duvall JR, Kihlberg J. Over B, et al. Among authors: kihlberg j. J Med Chem. 2014 Mar 27;57(6):2746-54. doi: 10.1021/jm500059t. Epub 2014 Feb 26. J Med Chem. 2014. PMID: 24524242 Free PMC article.
Cell permeability beyond the rule of 5.
Matsson P, Doak BC, Over B, Kihlberg J. Matsson P, et al. Among authors: kihlberg j. Adv Drug Deliv Rev. 2016 Jun 1;101:42-61. doi: 10.1016/j.addr.2016.03.013. Epub 2016 Apr 9. Adv Drug Deliv Rev. 2016. PMID: 27067608 Review.
Structural and conformational determinants of macrocycle cell permeability.
Over B, Matsson P, Tyrchan C, Artursson P, Doak BC, Foley MA, Hilgendorf C, Johnston SE, Lee MD 4th, Lewis RJ, McCarren P, Muncipinto G, Norinder U, Perry MW, Duvall JR, Kihlberg J. Over B, et al. Among authors: kihlberg j. Nat Chem Biol. 2016 Dec;12(12):1065-1074. doi: 10.1038/nchembio.2203. Epub 2016 Oct 17. Nat Chem Biol. 2016. PMID: 27748751
Drug discovery beyond the rule of 5 - Opportunities and challenges.
Doak BC, Kihlberg J. Doak BC, et al. Among authors: kihlberg j. Expert Opin Drug Discov. 2017 Feb;12(2):115-119. doi: 10.1080/17460441.2017.1264385. Epub 2016 Dec 8. Expert Opin Drug Discov. 2017. PMID: 27883294 No abstract available.
How Big Is Too Big for Cell Permeability?
Matsson P, Kihlberg J. Matsson P, et al. Among authors: kihlberg j. J Med Chem. 2017 Mar 9;60(5):1662-1664. doi: 10.1021/acs.jmedchem.7b00237. Epub 2017 Feb 24. J Med Chem. 2017. PMID: 28234469
201 results