Pazos F - Search Results

1

Biophysical and biochemical strategies to understand membrane binding and pore formation by sticholysins, pore-forming proteins from a sea anemone.

Alvarez C, Ros U, Valle A, Pedrera L, Soto C, Hervis YP, Cabezas S, Valiente PA, Pazos F, Lanio ME. Alvarez C, et al. Among authors: pazos f. Biophys Rev. 2017 Oct;9(5):529-544. doi: 10.1007/s12551-017-0316-0. Epub 2017 Aug 29. Biophys Rev. 2017. PMID: 28853034 Free PMC article. Review.

2

Sticholysins I and II interaction with cationic micelles promotes toxins' conformational changes and enhanced hemolytic activity.

Lanio ME, Alvarez C, Ochoa C, Ros U, Pazos F, Martínez D, Tejuca M, Eugenio LM, Casallanovo F, Dyszy FH, Schreier S, Lissi E. Lanio ME, et al. Among authors: pazos f. Toxicon. 2007 Nov;50(6):731-9. doi: 10.1016/j.toxicon.2007.06.007. Epub 2007 Jun 26. Toxicon. 2007. PMID: 17681582

3

Sticholysins, two pore-forming toxins produced by the Caribbean Sea anemone Stichodactyla helianthus: their interaction with membranes.

Alvarez C, Mancheño JM, Martínez D, Tejuca M, Pazos F, Lanio ME. Alvarez C, et al. Among authors: pazos f. Toxicon. 2009 Dec 15;54(8):1135-47. doi: 10.1016/j.toxicon.2009.02.022. Epub 2009 Mar 4. Toxicon. 2009. PMID: 19268489 Free article. Review.

4

Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins.

Pentón D, Pérez-Barzaga V, Díaz I, Reytor ML, Campos J, Fando R, Calvo L, Cilli EM, Morera V, Castellanos-Serra LR, Pazos F, Lanio ME, Alvarez C, Pons T, Tejuca M. Pentón D, et al. Among authors: pazos f. Protein Eng Des Sel. 2011 Jun;24(6):485-93. doi: 10.1093/protein/gzr002. Epub 2011 Feb 4. Protein Eng Des Sel. 2011. PMID: 21296830

5

The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as lipid composition.

Ros U, Pedrera L, Diaz D, Karam JC, Sudbrack TP, Valiente PA, MartÍnez D, Cilli EM, Pazos F, Itri R, Lanio ME, Schreier S, Ávarez C. Ros U, et al. Among authors: pazos f. J Biosci. 2011 Dec;36(5):781-91. doi: 10.1007/s12038-011-9156-4. J Biosci. 2011. PMID: 22116276

6

Functional and topological studies with Trp-containing analogs of the peptide StII(1-30) derived from the N-terminus of the pore forming toxin sticholysin II: contribution to understand its orientation in membrane.

Ros U, Souto AL, de Oliveira FJ, Crusca E Jr, Pazos F, Cilli EM, Lanio ME, Schreier S, Alvarez C. Ros U, et al. Among authors: pazos f. Biopolymers. 2013 Jul;100(4):337-46. doi: 10.1002/bip.22211. Biopolymers. 2013. PMID: 23868208

7

Sticholysin II-mediated cytotoxicity involves the activation of regulated intracellular responses that anticipates cell death.

Soto C, Bergado G, Blanco R, Griñán T, Rodríguez H, Ros U, Pazos F, Lanio ME, Hernández AM, Álvarez C. Soto C, et al. Among authors: pazos f. Biochimie. 2018 May;148:18-35. doi: 10.1016/j.biochi.2018.02.006. Epub 2018 Feb 13. Biochimie. 2018. PMID: 29452280

8

Self-association and folding in membrane determine the mode of action of peptides from the lytic segment of sticholysins.

Ros U, Carretero GPB, Paulino J, Crusca E Jr, Pazos F, Cilli EM, Lanio ME, Schreier S, Alvarez C. Ros U, et al. Among authors: pazos f. Biochimie. 2019 Jan;156:109-117. doi: 10.1016/j.biochi.2018.10.005. Epub 2018 Oct 13. Biochimie. 2019. PMID: 30326255

9

Sticholysins, pore-forming proteins from a marine anemone can induce maturation of dendritic cells through a TLR4 dependent-pathway.

Laborde RJ, Ishimura ME, Abreu-Butin L, Nogueira CV, Grubaugh D, Cruz-Leal Y, Luzardo MC, Fernández A, Mesa C, Pazos F, Álvarez C, Alonso ME, Starnbach MN, Higgins DE, Fernández LE, Longo-Maugéri IM, Lanio ME. Laborde RJ, et al. Among authors: pazos f. Mol Immunol. 2021 Mar;131:144-154. doi: 10.1016/j.molimm.2020.12.032. Epub 2021 Jan 6. Mol Immunol. 2021. PMID: 33422341

10

Panorama of the Intracellular Molecular Concert Orchestrated by Actinoporins, Pore-Forming Toxins from Sea Anemones.

Alvarez C, Soto C, Cabezas S, Alvarado-Mesén J, Laborde R, Pazos F, Ros U, Hernández AM, Lanio ME. Alvarez C, et al. Among authors: pazos f. Toxins (Basel). 2021 Aug 13;13(8):567. doi: 10.3390/toxins13080567. Toxins (Basel). 2021. PMID: 34437438 Free PMC article. Review.

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