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Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation.
Meier JC, Tallant C, Fedorov O, Witwicka H, Hwang SY, van Stiphout RG, Lambert JP, Rogers C, Yapp C, Gerstenberger BS, Fedele V, Savitsky P, Heidenreich D, Daniels DL, Owen DR, Fish PV, Igoe NM, Bayle ED, Haendler B, Oppermann UCT, Buffa F, Brennan PE, Müller S, Gingras AC, Odgren PR, Birnbaum MJ, Knapp S. Meier JC, et al. Among authors: haendler b. ACS Chem Biol. 2017 Oct 20;12(10):2619-2630. doi: 10.1021/acschembio.7b00481. Epub 2017 Sep 12. ACS Chem Biol. 2017. PMID: 28849908 Free PMC article.
U2 RNA shares a structural domain with U1, U4, and U5 RNAs.
Branlant C, Krol A, Ebel JP, Lazar E, Haendler B, Jacob M. Branlant C, et al. Among authors: haendler b. EMBO J. 1982;1(10):1259-65. doi: 10.1002/j.1460-2075.1982.tb00022.x. EMBO J. 1982. PMID: 6202507 Free PMC article.
Two 5S genes are expressed in chicken somatic cells.
Lazar E, Haendler B, Jacob M. Lazar E, et al. Among authors: haendler b. Nucleic Acids Res. 1983 Nov 25;11(22):7735-41. doi: 10.1093/nar/11.22.7735. Nucleic Acids Res. 1983. PMID: 6196721 Free PMC article.
Bromodomains and their pharmacological inhibitors.
Gallenkamp D, Gelato KA, Haendler B, Weinmann H. Gallenkamp D, et al. Among authors: haendler b. ChemMedChem. 2014 Mar;9(3):438-64. doi: 10.1002/cmdc.201300434. Epub 2014 Feb 4. ChemMedChem. 2014. PMID: 24497428 Review.
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C, Brennan PE, Müller S, Knapp S. Bennett J, et al. Among authors: haendler b. J Med Chem. 2016 Feb 25;59(4):1642-7. doi: 10.1021/acs.jmedchem.5b00458. Epub 2015 May 20. J Med Chem. 2016. PMID: 25974391 Free PMC article.
Targeting BET bromodomains for cancer treatment.
Jung M, Gelato KA, Fernández-Montalván A, Siegel S, Haendler B. Jung M, et al. Among authors: haendler b. Epigenomics. 2015;7(3):487-501. doi: 10.2217/epi.14.91. Epigenomics. 2015. PMID: 26077433 Review.
101 results