Lessnick SL - Search Results

1

Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth.

Johnson KM, Mahler NR, Saund RS, Theisen ER, Taslim C, Callender NW, Crow JC, Miller KR, Lessnick SL. Johnson KM, et al. Among authors: lessnick sl. Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9870-9875. doi: 10.1073/pnas.1701872114. Epub 2017 Aug 28. Proc Natl Acad Sci U S A. 2017. PMID: 28847958 Free PMC article.

2

Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting.

Theisen ER, Pishas KI, Saund RS, Lessnick SL. Theisen ER, et al. Among authors: lessnick sl. Oncotarget. 2016 Apr 5;7(14):17616-30. doi: 10.18632/oncotarget.7124. Oncotarget. 2016. PMID: 26848860 Free PMC article. Review.

3

Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.

Johnson KM, Taslim C, Saund RS, Lessnick SL. Johnson KM, et al. Among authors: lessnick sl. PLoS One. 2017 Nov 1;12(11):e0186275. doi: 10.1371/journal.pone.0186275. eCollection 2017. PLoS One. 2017. PMID: 29091716 Free PMC article.

4

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis.

Showpnil IA, Miller KR, Taslim C, Pishas KI, Lessnick SL, Theisen ER. Showpnil IA, et al. Among authors: lessnick sl. J Vis Exp. 2020 Jun 27;(160):10.3791/61564. doi: 10.3791/61564. J Vis Exp. 2020. PMID: 32658189 Free PMC article.

5

EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma.

Showpnil IA, Selich-Anderson J, Taslim C, Boone MA, Crow JC, Theisen ER, Lessnick SL. Showpnil IA, et al. Among authors: lessnick sl. Nucleic Acids Res. 2022 Sep 23;50(17):9814-9837. doi: 10.1093/nar/gkac747. Nucleic Acids Res. 2022. PMID: 36124657 Free PMC article.

6

Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.

Sankar S, Theisen ER, Bearss J, Mulvihill T, Hoffman LM, Sorna V, Beckerle MC, Sharma S, Lessnick SL. Sankar S, et al. Among authors: lessnick sl. Clin Cancer Res. 2014 Sep 1;20(17):4584-97. doi: 10.1158/1078-0432.CCR-14-0072. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963049 Free PMC article.

7

Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group.

Monument MJ, Johnson KM, McIlvaine E, Abegglen L, Watkins WS, Jorde LB, Womer RB, Beeler N, Monovich L, Lawlor ER, Bridge JA, Schiffman JD, Krailo MD, Randall RL, Lessnick SL. Monument MJ, et al. Among authors: lessnick sl. PLoS One. 2014 Aug 5;9(8):e104378. doi: 10.1371/journal.pone.0104378. eCollection 2014. PLoS One. 2014. PMID: 25093581 Free PMC article.

8

Therapeutic Targeting of KDM1A/LSD1 in Ewing Sarcoma with SP-2509 Engages the Endoplasmic Reticulum Stress Response.

Pishas KI, Drenberg CD, Taslim C, Theisen ER, Johnson KM, Saund RS, Pop IL, Crompton BD, Lawlor ER, Tirode F, Mora J, Delattre O, Beckerle MC, Callen DF, Sharma S, Lessnick SL. Pishas KI, et al. Among authors: lessnick sl. Mol Cancer Ther. 2018 Sep;17(9):1902-1916. doi: 10.1158/1535-7163.MCT-18-0373. Epub 2018 Jul 11. Mol Cancer Ther. 2018. PMID: 29997151 Free PMC article.

9

Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis.

Theisen ER, Miller KR, Showpnil IA, Taslim C, Pishas KI, Lessnick SL. Theisen ER, et al. Among authors: lessnick sl. Genes Cancer. 2019 Feb;10(1-2):21-38. doi: 10.18632/genesandcancer.188. Genes Cancer. 2019. PMID: 30899417 Free PMC article.

10

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma.

Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL. Patel PO, et al. Among authors: lessnick sl. Oncotarget. 2019 Jun 11;10(39):3865-3878. doi: 10.18632/oncotarget.26988. eCollection 2019 Jun 11. Oncotarget. 2019. PMID: 31231465 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

109 results

Search Page