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GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
Yang L, Chang CC, Sun Z, Madsen D, Zhu H, Padkjær SB, Wu X, Huang T, Hultman K, Paulsen SJ, Wang J, Bugge A, Frantzen JB, Nørgaard P, Jeppesen JF, Yang Z, Secher A, Chen H, Li X, John LM, Shan B, He Z, Gao X, Su J, Hansen KT, Yang W, Jørgensen SB. Yang L, et al. Among authors: su j. Nat Med. 2017 Oct;23(10):1158-1166. doi: 10.1038/nm.4394. Epub 2017 Aug 28. Nat Med. 2017. PMID: 28846099
Construction of a versatile expression library for all human single-pass transmembrane proteins for receptor pairings by high throughput screening.
Yang W, Padkjær SB, Wang J, Sun Z, Shan B, Yang L, Chen H, Kang L, Madsen D, Li X, Shen C, Yu B, Zhu H, Chao TY, Cao Z, Li D, Liu W, Du Y, Xu J, Hao D, Xu F, Peng L, Li T, Wang L, Li L, Xing H, Liu D, Liu Z, Guan Z, Wang W, Cheng H, Østergaard H, Chang C, Yang Z, Boel E, Su J. Yang W, et al. Among authors: su j. J Biotechnol. 2017 Oct 20;260:18-30. doi: 10.1016/j.jbiotec.2017.08.023. Epub 2017 Sep 1. J Biotechnol. 2017. PMID: 28867483
Long-Acting Human Growth Hormone Analogue by Noncovalent Albumin Binding.
Ramírez-Andersen HS, Behrens C, Buchardt J, Fels JJ, Folkesson CG, Jianhe C, Nørskov-Lauritsen L, Nielsen PF, Reslow M, Rischel C, Su J, Thygesen P, Wiberg C, Zhao X, Wenjuan X, Johansen NL. Ramírez-Andersen HS, et al. Among authors: su j. Bioconjug Chem. 2018 Sep 19;29(9):3129-3143. doi: 10.1021/acs.bioconjchem.8b00463. Epub 2018 Aug 31. Bioconjug Chem. 2018. PMID: 30168709
Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.
Andersen HS, Olsen OH, Iversen LF, Sørensen AL, Mortensen SB, Christensen MS, Branner S, Hansen TK, Lau JF, Jeppesen L, Moran EJ, Su J, Bakir F, Judge L, Shahbaz M, Collins T, Vo T, Newman MJ, Ripka WC, Møller NP. Andersen HS, et al. Among authors: su j. J Med Chem. 2002 Sep 26;45(20):4443-59. doi: 10.1021/jm0209026. J Med Chem. 2002. PMID: 12238924
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