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Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors.
Gonzalez-Cordero A, Kruczek K, Naeem A, Fernando M, Kloc M, Ribeiro J, Goh D, Duran Y, Blackford SJI, Abelleira-Hervas L, Sampson RD, Shum IO, Branch MJ, Gardner PJ, Sowden JC, Bainbridge JWB, Smith AJ, West EL, Pearson RA, Ali RR. Gonzalez-Cordero A, et al. Among authors: duran y. Stem Cell Reports. 2017 Sep 12;9(3):820-837. doi: 10.1016/j.stemcr.2017.07.022. Epub 2017 Aug 24. Stem Cell Reports. 2017. PMID: 28844659 Free PMC article.
Targeted disruption of outer limiting membrane junctional proteins (Crb1 and ZO-1) increases integration of transplanted photoreceptor precursors into the adult wild-type and degenerating retina.
Pearson RA, Barber AC, West EL, MacLaren RE, Duran Y, Bainbridge JW, Sowden JC, Ali RR. Pearson RA, et al. Among authors: duran y. Cell Transplant. 2010;19(4):487-503. doi: 10.3727/096368909X486057. Epub 2010 Jan 20. Cell Transplant. 2010. PMID: 20089206 Free PMC article.
Donor and host photoreceptors engage in material transfer following transplantation of post-mitotic photoreceptor precursors.
Pearson RA, Gonzalez-Cordero A, West EL, Ribeiro JR, Aghaizu N, Goh D, Sampson RD, Georgiadis A, Waldron PV, Duran Y, Naeem A, Kloc M, Cristante E, Kruczek K, Warre-Cornish K, Sowden JC, Smith AJ, Ali RR. Pearson RA, et al. Among authors: duran y. Nat Commun. 2016 Oct 4;7:13029. doi: 10.1038/ncomms13029. Nat Commun. 2016. PMID: 27701378 Free PMC article.
Photoreceptor precursors derived from three-dimensional embryonic stem cell cultures integrate and mature within adult degenerate retina.
Gonzalez-Cordero A, West EL, Pearson RA, Duran Y, Carvalho LS, Chu CJ, Naeem A, Blackford SJI, Georgiadis A, Lakowski J, Hubank M, Smith AJ, Bainbridge JWB, Sowden JC, Ali RR. Gonzalez-Cordero A, et al. Among authors: duran y. Nat Biotechnol. 2013 Aug;31(8):741-7. doi: 10.1038/nbt.2643. Epub 2013 Jul 21. Nat Biotechnol. 2013. PMID: 23873086 Free PMC article.
Differentiation and Transplantation of Embryonic Stem Cell-Derived Cone Photoreceptors into a Mouse Model of End-Stage Retinal Degeneration.
Kruczek K, Gonzalez-Cordero A, Goh D, Naeem A, Jonikas M, Blackford SJI, Kloc M, Duran Y, Georgiadis A, Sampson RD, Maswood RN, Smith AJ, Decembrini S, Arsenijevic Y, Sowden JC, Pearson RA, West EL, Ali RR. Kruczek K, et al. Among authors: duran y. Stem Cell Reports. 2017 Jun 6;8(6):1659-1674. doi: 10.1016/j.stemcr.2017.04.030. Epub 2017 May 25. Stem Cell Reports. 2017. PMID: 28552606 Free PMC article.
Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner.
Waldron PV, Di Marco F, Kruczek K, Ribeiro J, Graca AB, Hippert C, Aghaizu ND, Kalargyrou AA, Barber AC, Grimaldi G, Duran Y, Blackford SJI, Kloc M, Goh D, Zabala Aldunate E, Sampson RD, Bainbridge JWB, Smith AJ, Gonzalez-Cordero A, Sowden JC, Ali RR, Pearson RA. Waldron PV, et al. Among authors: duran y. Stem Cell Reports. 2018 Feb 13;10(2):406-421. doi: 10.1016/j.stemcr.2017.12.008. Epub 2018 Jan 4. Stem Cell Reports. 2018. PMID: 29307580 Free PMC article.
Restoration of vision after transplantation of photoreceptors.
Pearson RA, Barber AC, Rizzi M, Hippert C, Xue T, West EL, Duran Y, Smith AJ, Chuang JZ, Azam SA, Luhmann UF, Benucci A, Sung CH, Bainbridge JW, Carandini M, Yau KW, Sowden JC, Ali RR. Pearson RA, et al. Among authors: duran y. Nature. 2012 May 3;485(7396):99-103. doi: 10.1038/nature10997. Nature. 2012. PMID: 22522934 Free PMC article.
Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.
Georgiadis A, Duran Y, Ribeiro J, Abelleira-Hervas L, Robbie SJ, Sünkel-Laing B, Fourali S, Gonzalez-Cordero A, Cristante E, Michaelides M, Bainbridge JW, Smith AJ, Ali RR. Georgiadis A, et al. Among authors: duran y. Gene Ther. 2016 Dec;23(12):857-862. doi: 10.1038/gt.2016.66. Epub 2016 Sep 22. Gene Ther. 2016. PMID: 27653967 Free PMC article.
66 results