Hibbs DE - Search Results

1

Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X₇ Receptor Antagonist.

Wilkinson SM, Barron ML, O'Brien-Brown J, Janssen B, Stokes L, Werry EL, Chishty M, Skarratt KK, Ong JA, Hibbs DE, Vugts DJ, Fuller S, Windhorst AD, Kassiou M. Wilkinson SM, et al. Among authors: hibbs de. ACS Chem Neurosci. 2017 Nov 15;8(11):2374-2380. doi: 10.1021/acschemneuro.7b00272. Epub 2017 Aug 25. ACS Chem Neurosci. 2017. PMID: 28841278

2

Non-Antigenic Modulation of Antigen Receptor (TCR) Cβ-FG Loop Modulates Signalling: Implications of External Factors Influencing T-Cell Responses.

Manolios N, Pham S, Hou G, Du J, Quek C, Hibbs D. Manolios N, et al. Int J Mol Sci. 2023 May 26;24(11):9334. doi: 10.3390/ijms24119334. Int J Mol Sci. 2023. PMID: 37298286 Free PMC article.

3

A σ(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs).

Banister SD, Manoli M, Doddareddy MR, Hibbs DE, Kassiou M. Banister SD, et al. Among authors: hibbs de. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6053-8. doi: 10.1016/j.bmcl.2012.08.046. Epub 2012 Aug 21. Bioorg Med Chem Lett. 2012. PMID: 22959245

4

The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.

Banister SD, Wilkinson SM, Longworth M, Stuart J, Apetz N, English K, Brooker L, Goebel C, Hibbs DE, Glass M, Connor M, McGregor IS, Kassiou M. Banister SD, et al. Among authors: hibbs de. ACS Chem Neurosci. 2013 Jul 17;4(7):1081-92. doi: 10.1021/cn400035r. Epub 2013 Apr 17. ACS Chem Neurosci. 2013. PMID: 23551277 Free PMC article.

5

The multikinase inhibitor axitinib is a potent inhibitor of human CYP1A2.

Gu R, Hibbs DE, Ong JA, Edwards RJ, Murray M. Gu R, et al. Among authors: hibbs de. Biochem Pharmacol. 2014 Mar 15;88(2):245-52. doi: 10.1016/j.bcp.2014.01.016. Epub 2014 Jan 22. Biochem Pharmacol. 2014. PMID: 24462920

6

Effects of bioisosteric fluorine in synthetic cannabinoid designer drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135.

Banister SD, Stuart J, Kevin RC, Edington A, Longworth M, Wilkinson SM, Beinat C, Buchanan AS, Hibbs DE, Glass M, Connor M, McGregor IS, Kassiou M. Banister SD, et al. Among authors: hibbs de. ACS Chem Neurosci. 2015 Aug 19;6(8):1445-58. doi: 10.1021/acschemneuro.5b00107. Epub 2015 May 8. ACS Chem Neurosci. 2015. PMID: 25921407

7

Rapid access to N-(indol-2-yl)amides and N-(indol-3-yl)amides as unexplored pharmacophores.

Reekie TA, Wilkinson SM, Law V, Hibbs DE, Ong JA, Kassiou M. Reekie TA, et al. Among authors: hibbs de. Org Biomol Chem. 2017 Jan 18;15(3):576-580. doi: 10.1039/c6ob02622b. Org Biomol Chem. 2017. PMID: 27991628

8

Strategies to develop selective CB₂ receptor agonists from indole carboxamide synthetic cannabinoids.

Moir M, Lane S, Lai F, Connor M, Hibbs DE, Kassiou M. Moir M, et al. Among authors: hibbs de. Eur J Med Chem. 2019 Oct 15;180:291-309. doi: 10.1016/j.ejmech.2019.07.036. Epub 2019 Jul 11. Eur J Med Chem. 2019. PMID: 31319265

9

First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold.

Cheng HWA, Sokias R, Werry EL, Ittner LM, Reekie TA, Du J, Gao Q, Hibbs DE, Kassiou M. Cheng HWA, et al. Among authors: hibbs de. J Med Chem. 2019 Sep 12;62(17):8235-8248. doi: 10.1021/acs.jmedchem.9b00980. Epub 2019 Aug 28. J Med Chem. 2019. PMID: 31419132

10

Tricyclic heterocycles display diverse sensitivity to the A147T TSPO polymorphism.

Sokias R, Werry EL, Alison Cheng HW, Lloyd JH, Sohler G, Danon JJ, Montgomery AP, Du JJ, Gao Q, Hibbs DE, Ittner LM, Reekie TA, Kassiou M. Sokias R, et al. Among authors: hibbs de. Eur J Med Chem. 2020 Dec 1;207:112725. doi: 10.1016/j.ejmech.2020.112725. Epub 2020 Aug 15. Eur J Med Chem. 2020. PMID: 32920427

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