Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

491 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors.
Vettorazzi M, Angelina E, Lima S, Gonec T, Otevrel J, Marvanova P, Padrtova T, Mokry P, Bobal P, Acosta LM, Palma A, Cobo J, Bobalova J, Csollei J, Malik I, Alvarez S, Spiegel S, Jampilek J, Enriz RD. Vettorazzi M, et al. Among authors: spiegel s. Eur J Med Chem. 2017 Oct 20;139:461-481. doi: 10.1016/j.ejmech.2017.08.017. Epub 2017 Aug 10. Eur J Med Chem. 2017. PMID: 28822281 Free PMC article.
Stereospecificity of sphingosine-induced intracellular calcium mobilization and cellular proliferation.
Olivera A, Zhang H, Carlson RO, Mattie ME, Schmidt RR, Spiegel S. Olivera A, et al. Among authors: spiegel s. J Biol Chem. 1994 Jul 8;269(27):17924-30. J Biol Chem. 1994. PMID: 8027049 Free article.
Sphingosine is a positive regulator of cell growth in Swiss 3T3 fibroblasts (Zhang, H., Buckley, N. E., Gibson, K., and Spiegel, S. (1990) J. Biol. Chem. 265, 76-81). The present study investigated the stereospecificity of sphingosine-induced cell proliferation and …
Sphingosine is a positive regulator of cell growth in Swiss 3T3 fibroblasts (Zhang, H., Buckley, N. E., Gibson, K., and Spiegel, S …
Divergence in signal transduction pathways of platelet-derived growth factor (PDGF) and epidermal growth factor (EGF) receptors. Involvement of sphingosine 1-phosphate in PDGF but not EGF signaling.
Rani CS, Wang F, Fuior E, Berger A, Wu J, Sturgill TW, Beitner-Johnson D, LeRoith D, Varticovski L, Spiegel S. Rani CS, et al. Among authors: spiegel s. J Biol Chem. 1997 Apr 18;272(16):10777-83. doi: 10.1074/jbc.272.16.10777. J Biol Chem. 1997. PMID: 9099730 Free article.
Platelet-derived growth factor (PDGF) and serum, but not epidermal growth factor (EGF), stimulated sphingosine kinase activity in Swiss 3T3 fibroblasts and increased intracellular concentrations of sphingosine 1-phosphate (SPP), a sphingolipid second messenger (Olivera, A., and …
Platelet-derived growth factor (PDGF) and serum, but not epidermal growth factor (EGF), stimulated sphingosine kinase activity in Swiss 3T3 …
Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform.
Liu H, Sugiura M, Nava VE, Edsall LC, Kono K, Poulton S, Milstien S, Kohama T, Spiegel S. Liu H, et al. Among authors: spiegel s. J Biol Chem. 2000 Jun 30;275(26):19513-20. doi: 10.1074/jbc.M002759200. J Biol Chem. 2000. PMID: 10751414 Free article.
Based on sequence homology to murine and human sphingosine kinase-1 (SPHK1), which we recently cloned (Kohama, T., Oliver, A., Edsall, L. , Nagiec, M. M., Dickson, R., and Spiegel, S. (1998) J. Biol. Chem. 273, 23722-23728), we have now cloned a second type of mouse …
Based on sequence homology to murine and human sphingosine kinase-1 (SPHK1), which we recently cloned (Kohama, T., Oliver, A., Edsall, L. , …
Sphingosine 1-phosphate, a key cell signaling molecule.
Spiegel S, Milstien S. Spiegel S, et al. J Biol Chem. 2002 Jul 19;277(29):25851-4. doi: 10.1074/jbc.R200007200. Epub 2002 May 13. J Biol Chem. 2002. PMID: 12011102 Free article. Review. No abstract available.
491 results