Kalkan T - Search Results

1

A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation.

Li MA, Amaral PP, Cheung P, Bergmann JH, Kinoshita M, Kalkan T, Ralser M, Robson S, von Meyenn F, Paramor M, Yang F, Chen C, Nichols J, Spector DL, Kouzarides T, He L, Smith A. Li MA, et al. Among authors: kalkan t. Elife. 2017 Aug 18;6:e23468. doi: 10.7554/eLife.23468. Elife. 2017. PMID: 28820723 Free PMC article.

2

Mapping the route from naive pluripotency to lineage specification.

Kalkan T, Smith A. Kalkan T, et al. Philos Trans R Soc Lond B Biol Sci. 2014 Dec 5;369(1657):20130540. doi: 10.1098/rstb.2013.0540. Philos Trans R Soc Lond B Biol Sci. 2014. PMID: 25349449 Free PMC article. Review.

3

Tracking the embryonic stem cell transition from ground state pluripotency.

Kalkan T, Olova N, Roode M, Mulas C, Lee HJ, Nett I, Marks H, Walker R, Stunnenberg HG, Lilley KS, Nichols J, Reik W, Bertone P, Smith A. Kalkan T, et al. Development. 2017 Apr 1;144(7):1221-1234. doi: 10.1242/dev.142711. Epub 2017 Feb 7. Development. 2017. PMID: 28174249 Free PMC article.

4

NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State.

Mulas C, Kalkan T, Smith A. Mulas C, et al. Among authors: kalkan t. Stem Cell Reports. 2017 Jul 11;9(1):77-91. doi: 10.1016/j.stemcr.2017.05.033. Epub 2017 Jun 29. Stem Cell Reports. 2017. PMID: 28669603 Free PMC article.

5

The ground state of pluripotency.

Wray J, Kalkan T, Smith AG. Wray J, et al. Among authors: kalkan t. Biochem Soc Trans. 2010 Aug;38(4):1027-32. doi: 10.1042/BST0381027. Biochem Soc Trans. 2010. PMID: 20658998 Review.

6

Defined conditions for propagation and manipulation of mouse embryonic stem cells.

Mulas C, Kalkan T, von Meyenn F, Leitch HG, Nichols J, Smith A. Mulas C, et al. Among authors: kalkan t. Development. 2019 Mar 26;146(6):dev173146. doi: 10.1242/dev.173146. Development. 2019. PMID: 30914406 Free PMC article.

7

Complementary Activity of ETV5, RBPJ, and TCF3 Drives Formative Transition from Naive Pluripotency.

Kalkan T, Bornelöv S, Mulas C, Diamanti E, Lohoff T, Ralser M, Middelkamp S, Lombard P, Nichols J, Smith A. Kalkan T, et al. Cell Stem Cell. 2019 May 2;24(5):785-801.e7. doi: 10.1016/j.stem.2019.03.017. Epub 2019 Apr 25. Cell Stem Cell. 2019. PMID: 31031137 Free PMC article.

8

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation.

Wray J, Kalkan T, Gomez-Lopez S, Eckardt D, Cook A, Kemler R, Smith A. Wray J, et al. Among authors: kalkan t. Nat Cell Biol. 2011 Jun 19;13(7):838-45. doi: 10.1038/ncb2267. Nat Cell Biol. 2011. PMID: 21685889 Free PMC article.

9

The transcriptional and epigenomic foundations of ground state pluripotency.

Marks H, Kalkan T, Menafra R, Denissov S, Jones K, Hofemeister H, Nichols J, Kranz A, Stewart AF, Smith A, Stunnenberg HG. Marks H, et al. Among authors: kalkan t. Cell. 2012 Apr 27;149(3):590-604. doi: 10.1016/j.cell.2012.03.026. Cell. 2012. PMID: 22541430 Free PMC article.

10

A genome-wide RNAi screen reveals MAP kinase phosphatases as key ERK pathway regulators during embryonic stem cell differentiation.

Yang SH, Kalkan T, Morrisroe C, Smith A, Sharrocks AD. Yang SH, et al. Among authors: kalkan t. PLoS Genet. 2012;8(12):e1003112. doi: 10.1371/journal.pgen.1003112. Epub 2012 Dec 13. PLoS Genet. 2012. PMID: 23271975 Free PMC article.

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