Spring DR - Search Results

1

Targeting the Genome-Stability Hub Ctf4 by Stapled-Peptide Design.

Wu Y, Villa F, Maman J, Lau YH, Dobnikar L, Simon AC, Labib K, Spring DR, Pellegrini L. Wu Y, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2017 Oct 9;56(42):12866-12872. doi: 10.1002/anie.201705611. Epub 2017 Sep 7. Angew Chem Int Ed Engl. 2017. PMID: 28815832

2

Synthesis of medium-ring and iodinated biaryl compounds by organocuprate oxidation.

Surry DS, Su X, Fox DJ, Franckevicius V, Macdonald SJ, Spring DR. Surry DS, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2005 Mar 11;44(12):1870-3. doi: 10.1002/anie.200462642. Angew Chem Int Ed Engl. 2005. PMID: 15704230 No abstract available.

3

Anti-MRSA agent discovery using diversity-oriented synthesis.

Thomas GL, Spandl RJ, Glansdorp FG, Welch M, Bender A, Cockfield J, Lindsay JA, Bryant C, Brown DF, Loiseleur O, Rudyk H, Ladlow M, Spring DR. Thomas GL, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2008;47(15):2808-12. doi: 10.1002/anie.200705415. Angew Chem Int Ed Engl. 2008. PMID: 18307176 No abstract available.

4

Synthesis of unprecedented scaffold diversity.

Galloway WR, Diáz-Gavilán M, Isidro-Llobet A, Spring DR. Galloway WR, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2009;48(7):1194-6. doi: 10.1002/anie.200805452. Angew Chem Int Ed Engl. 2009. PMID: 19137520

5

Using ligand-mapping simulations to design a ligand selectively targeting a cryptic surface pocket of polo-like kinase 1.

Tan YS, Śledź P, Lang S, Stubbs CJ, Spring DR, Abell C, Best RB. Tan YS, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2012 Oct 1;51(40):10078-81. doi: 10.1002/anie.201205676. Epub 2012 Sep 7. Angew Chem Int Ed Engl. 2012. PMID: 22961729 Free PMC article. No abstract available.

6

Investigating peptide sequence variations for 'double-click' stapled p53 peptides.

Lau YH, de Andrade P, Sköld N, McKenzie GJ, Venkitaraman AR, Verma C, Lane DP, Spring DR. Lau YH, et al. Among authors: spring dr. Org Biomol Chem. 2014 Jun 28;12(24):4074-7. doi: 10.1039/c4ob00742e. Org Biomol Chem. 2014. PMID: 24817343

7

Peptide stapling techniques based on different macrocyclisation chemistries.

Lau YH, de Andrade P, Wu Y, Spring DR. Lau YH, et al. Among authors: spring dr. Chem Soc Rev. 2015 Jan 7;44(1):91-102. doi: 10.1039/c4cs00246f. Epub 2014 Sep 8. Chem Soc Rev. 2015. PMID: 25199043 Review.

8

Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy.

Grossmann A, Bartlett S, Janecek M, Hodgkinson JT, Spring DR. Grossmann A, et al. Among authors: spring dr. Angew Chem Int Ed Engl. 2014 Nov 24;53(48):13093-7. doi: 10.1002/anie.201406865. Epub 2014 Sep 26. Angew Chem Int Ed Engl. 2014. PMID: 25257387

9

Linear aliphatic dialkynes as alternative linkers for double-click stapling of p53-derived peptides.

Lau YH, de Andrade P, McKenzie GJ, Venkitaraman AR, Spring DR. Lau YH, et al. Among authors: spring dr. Chembiochem. 2014 Dec 15;15(18):2680-3. doi: 10.1002/cbic.201402374. Epub 2014 Oct 29. Chembiochem. 2014. PMID: 25354189

10

A two-component 'double-click' approach to peptide stapling.

Lau YH, Wu Y, de Andrade P, Galloway WR, Spring DR. Lau YH, et al. Among authors: spring dr. Nat Protoc. 2015 Apr;10(4):585-94. doi: 10.1038/nprot.2015.033. Epub 2015 Mar 12. Nat Protoc. 2015. PMID: 25763835

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