Boshoff HIM - Search Results

1

Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.

Santa Maria JP Jr, Park Y, Yang L, Murgolo N, Altman MD, Zuck P, Adam G, Chamberlin C, Saradjian P, Dandliker P, Boshoff HIM, Barry CE 3rd, Garlisi C, Olsen DB, Young K, Glick M, Nickbarg E, Kutchukian PS. Santa Maria JP Jr, et al. Among authors: boshoff him. ACS Chem Biol. 2017 Sep 15;12(9):2448-2456. doi: 10.1021/acschembio.7b00468. Epub 2017 Aug 29. ACS Chem Biol. 2017. PMID: 28806050 Free PMC article.

2

Effects of pyrazinamide on fatty acid synthesis by whole mycobacterial cells and purified fatty acid synthase I.

Boshoff HI, Mizrahi V, Barry CE 3rd. Boshoff HI, et al. J Bacteriol. 2002 Apr;184(8):2167-72. doi: 10.1128/JB.184.8.2167-2172.2002. J Bacteriol. 2002. PMID: 11914348 Free PMC article.

3

Top down characterization of secreted proteins from Mycobacterium tuberculosis by electron capture dissociation mass spectrometry.

Ge Y, El-Naggar M, Sze SK, Oh HB, Begley TP, McLafferty FW, Boshoff H, Barry CE 3rd. Ge Y, et al. J Am Soc Mass Spectrom. 2003 Mar;14(3):253-61. doi: 10.1016/s1044-0305(02)00913-3. J Am Soc Mass Spectrom. 2003. PMID: 12648932 Free article.

4

DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis.

Boshoff HI, Reed MB, Barry CE 3rd, Mizrahi V. Boshoff HI, et al. Cell. 2003 Apr 18;113(2):183-93. doi: 10.1016/s0092-8674(03)00270-8. Cell. 2003. PMID: 12705867 Free article.

5

The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice.

Dahl JL, Kraus CN, Boshoff HI, Doan B, Foley K, Avarbock D, Kaplan G, Mizrahi V, Rubin H, Barry CE 3rd. Dahl JL, et al. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10026-31. doi: 10.1073/pnas.1631248100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897239 Free PMC article.

6

The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.

Boshoff HI, Myers TG, Copp BR, McNeil MR, Wilson MA, Barry CE 3rd. Boshoff HI, et al. J Biol Chem. 2004 Sep 17;279(38):40174-84. doi: 10.1074/jbc.M406796200. Epub 2004 Jul 9. J Biol Chem. 2004. PMID: 15247240 Free article.

7

Prospects for clinical introduction of nitroimidazole antibiotics for the treatment of tuberculosis.

Barry CE 3rd, Boshoff HI, Dowd CS. Barry CE 3rd, et al. Curr Pharm Des. 2004;10(26):3239-62. doi: 10.2174/1381612043383214. Curr Pharm Des. 2004. PMID: 15544513 Review.

8

Tuberculosis - metabolism and respiration in the absence of growth.

Boshoff HI, Barry CE 3rd. Boshoff HI, et al. Nat Rev Microbiol. 2005 Jan;3(1):70-80. doi: 10.1038/nrmicro1065. Nat Rev Microbiol. 2005. PMID: 15608701 Review.

9

A low-carb diet for a high-octane pathogen.

Boshoff HI, Barry CE. Boshoff HI, et al. Nat Med. 2005 Jun;11(6):599-600. doi: 10.1038/nm0605-599. Nat Med. 2005. PMID: 15937469 No abstract available.

10

In vivo phenotypic dominance in mouse mixed infections with Mycobacterium tuberculosis clinical isolates.

Barczak AK, Domenech P, Boshoff HI, Reed MB, Manca C, Kaplan G, Barry CE 3rd. Barczak AK, et al. J Infect Dis. 2005 Aug 15;192(4):600-6. doi: 10.1086/432006. Epub 2005 Jul 7. J Infect Dis. 2005. PMID: 16028128

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