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Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells.
Lundberg L, Pinkham C, de la Fuente C, Brahms A, Shafagati N, Wagstaff KM, Jans DA, Tamir S, Kehn-Hall K. Lundberg L, et al. Among authors: brahms a. PLoS Negl Trop Dis. 2016 Nov 30;10(11):e0005122. doi: 10.1371/journal.pntd.0005122. eCollection 2016 Nov. PLoS Negl Trop Dis. 2016. PMID: 27902702 Free PMC article.
Rapamycin modulation of p70 S6 kinase signaling inhibits Rift Valley fever virus pathogenesis.
Bell TM, Espina V, Senina S, Woodson C, Brahms A, Carey B, Lin SC, Lundberg L, Pinkham C, Baer A, Mueller C, Chlipala EA, Sharman F, de la Fuente C, Liotta L, Kehn-Hall K. Bell TM, et al. Among authors: brahms a. Antiviral Res. 2017 Jul;143:162-175. doi: 10.1016/j.antiviral.2017.04.011. Epub 2017 Apr 23. Antiviral Res. 2017. PMID: 28442428 Free PMC article.
HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.
Alem F, Brahms A, Tarasaki K, Omole S, Kehn-Hall K, Schmaljohn CS, Bavari S, Makino S, Hakami RM. Alem F, et al. Among authors: brahms a. Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38800833 Free PMC article.
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