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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Bonetti L, Horkova V, Longworth J, Guerra L, Kurniawan H, Franchina DG, Soriano-Baguet L, Grusdat M, Spath S, Koncina E, Ewen A, Binsfeld C, Verschueren C, Gérardy JJ, Kobayashi T, Dostert C, Farinelle S, Härm J, Chen Y, Harris IS, Lang PA, Vasiliou V, Waisman A, Letellier E, Becher B, Mittelbronn M, Brenner D. Bonetti L, et al. Among authors: spath s. bioRxiv [Preprint]. 2023 Jul 7:2023.07.06.547932. doi: 10.1101/2023.07.06.547932. bioRxiv. 2023. PMID: 37489135 Free PMC article. Preprint.
FOXP3 exon 2 controls Treg stability and autoimmunity.
Du J, Wang Q, Yang S, Chen S, Fu Y, Spath S, Domeier P, Hagin D, Anover-Sombke S, Haouili M, Liu S, Wan J, Han L, Liu J, Yang L, Sangani N, Li Y, Lu X, Janga SC, Kaplan MH, Torgerson TR, Ziegler SF, Zhou B. Du J, et al. Among authors: spath s. Sci Immunol. 2022 Jun 24;7(72):eabo5407. doi: 10.1126/sciimmunol.abo5407. Epub 2022 Jun 24. Sci Immunol. 2022. PMID: 35749515 Free PMC article.
Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.
Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B. Tugues S, et al. Among authors: spath s. Sci Transl Med. 2018 Nov 28;10(469):eaat8410. doi: 10.1126/scitranslmed.aat8410. Sci Transl Med. 2018. PMID: 30487251
48 results