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Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Ellisdon AM, Nold-Petry CA, D'Andrea L, Cho SX, Lao JC, Rudloff I, Ngo D, Lo CY, Soares da Costa TP, Perugini MA, Conroy PJ, Whisstock JC, Nold MF. Ellisdon AM, et al. Among authors: conroy pj. Sci Immunol. 2017 Feb 10;2(8):eaaj1548. doi: 10.1126/sciimmunol.aaj1548. Sci Immunol. 2017. PMID: 28783685
Reconciling the structural attributes of avian antibodies.
Conroy PJ, Law RH, Gilgunn S, Hearty S, Caradoc-Davies TT, Lloyd G, O'Kennedy RJ, Whisstock JC. Conroy PJ, et al. J Biol Chem. 2014 May 30;289(22):15384-92. doi: 10.1074/jbc.M114.562470. Epub 2014 Apr 15. J Biol Chem. 2014. PMID: 24737329 Free PMC article.
Structure of the poly-C9 component of the complement membrane attack complex.
Dudkina NV, Spicer BA, Reboul CF, Conroy PJ, Lukoyanova N, Elmlund H, Law RH, Ekkel SM, Kondos SC, Goode RJ, Ramm G, Whisstock JC, Saibil HR, Dunstone MA. Dudkina NV, et al. Among authors: conroy pj. Nat Commun. 2016 Feb 4;7:10588. doi: 10.1038/ncomms10588. Nat Commun. 2016. PMID: 26841934 Free PMC article.
Perforin-A key (shaped) weapon in the immunological arsenal.
Spicer BA, Conroy PJ, Law RHP, Voskoboinik I, Whisstock JC. Spicer BA, et al. Among authors: conroy pj. Semin Cell Dev Biol. 2017 Dec;72:117-123. doi: 10.1016/j.semcdb.2017.07.033. Epub 2017 Jul 27. Semin Cell Dev Biol. 2017. PMID: 28757431 Review.
X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors.
Law RHP, Wu G, Leung EWW, Hidaka K, Quek AJ, Caradoc-Davies TT, Jeevarajah D, Conroy PJ, Kirby NM, Norton RS, Tsuda Y, Whisstock JC. Law RHP, et al. Among authors: conroy pj. Blood Adv. 2017 May 9;1(12):766-771. doi: 10.1182/bloodadvances.2016004150. eCollection 2017 May 9. Blood Adv. 2017. PMID: 29296720 Free PMC article.
55 results