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A Concise Synthesis of Forskolin.
Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12586-12589. doi: 10.1002/anie.201706809. Epub 2017 Sep 5.
Angew Chem Int Ed Engl. 2017.
PMID: 28782270
Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.
Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, Paruch K, Trbusek M.
Zemanova J, et al. Among authors: hylse o.
Oncotarget. 2016 Sep 20;7(38):62091-62106. doi: 10.18632/oncotarget.11388.
Oncotarget. 2016.
PMID: 27556692
Free PMC article.
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Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides.
Maier L, Khirsariya P, Hylse O, Adla SK, Černová L, Poljak M, Krajčovičová S, Weis E, Drápela S, Souček K, Paruch K.
Maier L, et al. Among authors: hylse o.
J Org Chem. 2017 Apr 7;82(7):3382-3402. doi: 10.1021/acs.joc.6b02594. Epub 2017 Mar 20.
J Org Chem. 2017.
PMID: 28267331
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Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Samadder P, Suchánková T, Hylse O, Khirsariya P, Nikulenkov F, Drápela S, Straková N, Vaňhara P, Vašíčková K, Kolářová H, Binó L, Bittová M, Ovesná P, Kollár P, Fedr R, Ešner M, Jaroš J, Hampl A, Krejčí L, Paruch K, Souček K.
Samadder P, et al. Among authors: hylse o.
Mol Cancer Ther. 2017 Sep;16(9):1831-1842. doi: 10.1158/1535-7163.MCT-17-0018. Epub 2017 Jun 15.
Mol Cancer Ther. 2017.
PMID: 28619751
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BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors.
Paculová H, Kramara J, Šimečková Š, Fedr R, Souček K, Hylse O, Paruch K, Svoboda M, Mistrík M, Kohoutek J.
Paculová H, et al. Among authors: hylse o.
Tumour Biol. 2017 Oct;39(10):1010428317727479. doi: 10.1177/1010428317727479.
Tumour Biol. 2017.
PMID: 29025359
Free article.
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Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules.
Szczepanik PM, Mikhaylov AA, Hylse O, Kučera R, Daďová P, Nečas M, Kubala L, Paruch K, Švenda J.
Szczepanik PM, et al. Among authors: hylse o.
Angew Chem Int Ed Engl. 2023 Jan 2;62(1):e202213183. doi: 10.1002/anie.202213183. Epub 2022 Nov 29.
Angew Chem Int Ed Engl. 2023.
PMID: 36321750
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