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Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilm formation, potentially contributing to cystic fibrosis pathogenesis.
Tynan A, Mawhinney L, Armstrong ME, O'Reilly C, Kennedy S, Caraher E, Jülicher K, O'Dwyer D, Maher L, Schaffer K, Fabre A, McKone EF, Leng L, Bucala R, Bernhagen J, Cooke G, Donnelly SC. Tynan A, et al. Among authors: leng l. FASEB J. 2017 Nov;31(11):5102-5110. doi: 10.1096/fj.201700463R. Epub 2017 Aug 2. FASEB J. 2017. PMID: 28768722 Free PMC article.
Our novel findings support the concept of an anti-MIF strategy that targets this enzymatic activity as a potential future antibacterial therapeutic approach.-Tynan, A., Mawhinney, L., Armstrong, M. E., O'Reilly, C., Kennedy, S., Caraher, E., Julicher, K., O'Dwyer, D., Mahe …
Our novel findings support the concept of an anti-MIF strategy that targets this enzymatic activity as a potential future antibacterial ther …
MIF signal transduction initiated by binding to CD74.
Leng L, Metz CN, Fang Y, Xu J, Donnelly S, Baugh J, Delohery T, Chen Y, Mitchell RA, Bucala R. Leng L, et al. J Exp Med. 2003 Jun 2;197(11):1467-76. doi: 10.1084/jem.20030286. J Exp Med. 2003. PMID: 12782713 Free PMC article.
Reduction of the aortic inflammatory response in spontaneous atherosclerosis by blockade of macrophage migration inhibitory factor (MIF).
Burger-Kentischer A, Göbel H, Kleemann R, Zernecke A, Bucala R, Leng L, Finkelmeier D, Geiger G, Schaefer HE, Schober A, Weber C, Brunner H, Rütten H, Ihling C, Bernhagen J. Burger-Kentischer A, et al. Among authors: leng l. Atherosclerosis. 2006 Jan;184(1):28-38. doi: 10.1016/j.atherosclerosis.2005.03.028. Atherosclerosis. 2006. PMID: 15921687
Simultaneous detection of microsatellite repeats and SNPs in the macrophage migration inhibitory factor (MIF) gene by thin-film biosensor chips and application to rural field studies.
Zhong XB, Leng L, Beitin A, Chen R, McDonald C, Hsiao B, Jenison RD, Kang I, Park SH, Lee A, Gregersen P, Thuma P, Bray-Ward P, Ward DC, Bucala R. Zhong XB, et al. Among authors: leng l. Nucleic Acids Res. 2005 Aug 2;33(13):e121. doi: 10.1093/nar/gni123. Nucleic Acids Res. 2005. PMID: 16077028 Free PMC article.
708 results