Prabhu VV - Search Results

1

Cancer stem cell-related gene expression as a potential biomarker of response for first-in-class imipridone ONC201 in solid tumors.

Prabhu VV, Lulla AR, Madhukar NS, Ralff MD, Zhao D, Kline CLB, Van den Heuvel APJ, Lev A, Garnett MJ, McDermott U, Benes CH, Batchelor TT, Chi AS, Elemento O, Allen JE, El-Deiry WS. Prabhu VV, et al. PLoS One. 2017 Aug 2;12(8):e0180541. doi: 10.1371/journal.pone.0180541. eCollection 2017. PLoS One. 2017. PMID: 28767654 Free PMC article.

2

CTGF-mediated autophagy-senescence transition in tumor stroma promotes anabolic tumor growth and metastasis.

Prabhu VV, Warfel NA, El-Deiry WS. Prabhu VV, et al. Cell Cycle. 2012 Jul 15;11(14):2592-3. doi: 10.4161/cc.21240. Epub 2012 Jul 15. Cell Cycle. 2012. PMID: 22751431 Free PMC article.

3

Therapeutic targeting of the p53 pathway in cancer stem cells.

Prabhu VV, Allen JE, Hong B, Zhang S, Cheng H, El-Deiry WS. Prabhu VV, et al. Expert Opin Ther Targets. 2012 Dec;16(12):1161-74. doi: 10.1517/14728222.2012.726985. Epub 2012 Sep 24. Expert Opin Ther Targets. 2012. PMID: 22998602 Free PMC article. Review.

4

Novel antineoplastics targeting genetic changes in colorectal cancer.

Joudeh J, Allen JE, Das A, Prabhu V, Farbaniec M, Adler J, El-Deiry WS. Joudeh J, et al. Adv Exp Med Biol. 2013;779:1-34. doi: 10.1007/978-1-4614-6176-0_1. Adv Exp Med Biol. 2013. PMID: 23288633 Review.

5

Prodigiosin rescues deficient p53 signaling and antitumor effects via upregulating p73 and disrupting its interaction with mutant p53.

Hong B, Prabhu VV, Zhang S, van den Heuvel AP, Dicker DT, Kopelovich L, El-Deiry WS. Hong B, et al. Among authors: prabhu vv. Cancer Res. 2014 Feb 15;74(4):1153-65. doi: 10.1158/0008-5472.CAN-13-0955. Epub 2013 Nov 18. Cancer Res. 2014. PMID: 24247721 Free PMC article.

6

Targeting tumor suppressor p53 for cancer therapy: strategies, challenges and opportunities.

Hong B, van den Heuvel AP, Prabhu VV, Zhang S, El-Deiry WS. Hong B, et al. Among authors: prabhu vv. Curr Drug Targets. 2014 Jan;15(1):80-9. doi: 10.2174/1389450114666140106101412. Curr Drug Targets. 2014. PMID: 24387333 Review.

7

COX-2 drives metastatic breast cells from brain lesions into the cerebrospinal fluid and systemic circulation.

Allen JE, Patel AS, Prabhu VV, Dicker DT, Sheehan JM, Glantz MJ, El-Deiry WS. Allen JE, et al. Among authors: prabhu vv. Cancer Res. 2014 May 1;74(9):2385-90. doi: 10.1158/0008-5472.CAN-13-2660. Epub 2014 Mar 10. Cancer Res. 2014. PMID: 24614081

8

Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10.

Allen JE, Prabhu VV, Talekar M, van den Heuvel AP, Lim B, Dicker DT, Fritz JL, Beck A, El-Deiry WS. Allen JE, et al. Among authors: prabhu vv. Cancer Res. 2015 Apr 15;75(8):1668-74. doi: 10.1158/0008-5472.CAN-14-2356. Epub 2015 Feb 13. Cancer Res. 2015. PMID: 25681273 Free PMC article.

9

Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner.

Prabhu VV, Allen JE, Dicker DT, El-Deiry WS. Prabhu VV, et al. Cancer Res. 2015 Apr 1;75(7):1423-32. doi: 10.1158/0008-5472.CAN-13-3451. Epub 2015 Feb 20. Cancer Res. 2015. PMID: 25712124 Free PMC article.

10

4th international conference on tumor progression and therapeutic resistance: meeting report.

Prabhu VV, El-Deiry WS. Prabhu VV, et al. Cancer Biol Ther. 2015;16(3):363-76. doi: 10.1080/15384047.2015.1004928. Cancer Biol Ther. 2015. PMID: 25782066 Free PMC article.

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