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The exocyst subunit Sec3 is regulated by a protein quality control pathway.
J Biol Chem. 2017 Sep 15;292(37):15240-15253. doi: 10.1074/jbc.M117.789867. Epub 2017 Aug 1.
J Biol Chem. 2017.
PMID: 28765280
Free PMC article.
Protein stability and degradation in health and disease.
Clausen L, Abildgaard AB, Gersing SK, Stein A, Lindorff-Larsen K, Hartmann-Petersen R.
Clausen L, et al. Among authors: abildgaard ab.
Adv Protein Chem Struct Biol. 2019;114:61-83. doi: 10.1016/bs.apcsb.2018.09.002. Epub 2018 Nov 28.
Adv Protein Chem Struct Biol. 2019.
PMID: 30635086
Review.
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Computational and cellular studies reveal structural destabilization and degradation of MLH1 variants in Lynch syndrome.
Abildgaard AB, Stein A, Nielsen SV, Schultz-Knudsen K, Papaleo E, Shrikhande A, Hoffmann ER, Bernstein I, Gerdes AM, Takahashi M, Ishioka C, Lindorff-Larsen K, Hartmann-Petersen R.
Abildgaard AB, et al.
Elife. 2019 Nov 7;8:e49138. doi: 10.7554/eLife.49138.
Elife. 2019.
PMID: 31697235
Free PMC article.
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Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome.
Abildgaard AB, Gersing SK, Larsen-Ledet S, Nielsen SV, Stein A, Lindorff-Larsen K, Hartmann-Petersen R.
Abildgaard AB, et al.
Biomolecules. 2020 Aug 4;10(8):1141. doi: 10.3390/biom10081141.
Biomolecules. 2020.
PMID: 32759676
Free PMC article.
Review.
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Lynch syndrome, molecular mechanisms and variant classification.
Abildgaard AB, Nielsen SV, Bernstein I, Stein A, Lindorff-Larsen K, Hartmann-Petersen R.
Abildgaard AB, et al.
Br J Cancer. 2023 Mar;128(5):726-734. doi: 10.1038/s41416-022-02059-z. Epub 2022 Nov 24.
Br J Cancer. 2023.
PMID: 36434153
Free PMC article.
Review.
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HSP70-binding motifs function as protein quality control degrons.
Abildgaard AB, Voutsinos V, Petersen SD, Larsen FB, Kampmeyer C, Johansson KE, Stein A, Ravid T, Andréasson C, Jensen MK, Lindorff-Larsen K, Hartmann-Petersen R.
Abildgaard AB, et al.
Cell Mol Life Sci. 2023 Jan 7;80(1):32. doi: 10.1007/s00018-022-04679-3.
Cell Mol Life Sci. 2023.
PMID: 36609589
Free PMC article.
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