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Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.
Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Rosendahl J, et al. Among authors: griesmann h. Gut. 2018 Oct;67(10):1855-1863. doi: 10.1136/gutjnl-2017-314454. Epub 2017 Jul 28. Gut. 2018. PMID: 28754779 Free PMC article.
Claudin-4 as therapeutic target in cancer.
Neesse A, Griesmann H, Gress TM, Michl P. Neesse A, et al. Among authors: griesmann h. Arch Biochem Biophys. 2012 Aug 1;524(1):64-70. doi: 10.1016/j.abb.2012.01.009. Epub 2012 Jan 24. Arch Biochem Biophys. 2012. PMID: 22286027 Review.
Common variants in the CLDN2-MORC4 and PRSS1-PRSS2 loci confer susceptibility to acute pancreatitis.
Weiss FU, Hesselbarth N, Párniczky A, Mosztbacher D, Lämmerhirt F, Ruffert C, Kovacs P, Beer S, Seltsam K, Griesmann H, Böhme R, Kaune T, Hollenbach M, Schulz HU, Simon P, Mayerle J, Lerch MM, Cavestro GM, Zuppardo RA, Di Leo M, Testoni PA, Malecka-Panas E, Gasirowska A, Głuszek S, Bugert P, Szentesi A, Mössner J, Witt H, Michl P, Hégyi P, Scholz M, Rosendahl J. Weiss FU, et al. Among authors: griesmann h. Pancreatology. 2018 Jul;18(5):477-481. doi: 10.1016/j.pan.2018.05.486. Epub 2018 Jun 1. Pancreatology. 2018. PMID: 29884332
Common variants in glyoxalase I do not increase chronic pancreatitis risk.
Kaune T, Hollenbach M, Keil B, Chen JM, Masson E, Becker C, Damm M, Ruffert C, Grützmann R, Hoffmeister A, Te Morsche RHM, Cavestro GM, Zuppardo RA, Saftoiu A, Malecka-Panas E, Głuszek S, Bugert P, Lerch MM, Weiss FU, Zou WB, Liao Z, Hegyi P, Drenth JP, Riedel J, Férec C, Scholz M, Kirsten H, Tóth A, Ewers M, Witt H, Griesmann H, Michl P, Rosendahl J. Kaune T, et al. Among authors: griesmann h. PLoS One. 2019 Oct 29;14(10):e0222927. doi: 10.1371/journal.pone.0222927. eCollection 2019. PLoS One. 2019. PMID: 31661534 Free PMC article.
Analysis of GPRC6A variants in different pancreatitis etiologies.
Kaune T, Ruffert C, Hesselbarth N, Damm M, Krug S, Cardinal von Widdern J, Masson E, Chen JM, Rebours V, Buscail L, Férec C, Grützmann R, Te Morsche RHM, Drenth JP, Cavestro GM, Zuppardo RA, Saftoiu A, Malecka-Panas E, Głuszek S, Bugert P, Lerch MM, Sendler M, Weiss FU, Zou WB, Deng SJ, Liao Z, Scholz M, Kirsten H, Hegyi P, Witt H, Michl P, Griesmann H, Rosendahl J. Kaune T, et al. Among authors: griesmann h. Pancreatology. 2020 Oct;20(7):1262-1267. doi: 10.1016/j.pan.2020.08.001. Epub 2020 Aug 8. Pancreatology. 2020. PMID: 32859544
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