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Translational Stroke Research: Vision and Opportunities.
Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W. Bosetti F, et al. Among authors: kohn h. Stroke. 2017 Sep;48(9):2632-2637. doi: 10.1161/STROKEAHA.117.017112. Epub 2017 Jul 27. Stroke. 2017. PMID: 28751554 Free PMC article. Review. No abstract available.
The anticonvulsant activities of N-benzyl 3-methoxypropionamides.
Andurkar SV, Stables JP, Kohn H. Andurkar SV, et al. Among authors: kohn h. Bioorg Med Chem. 1999 Nov;7(11):2381-9. doi: 10.1016/s0968-0896(99)00186-8. Bioorg Med Chem. 1999. PMID: 10632047
We recently reported that the ED50 value for (R,S)-2,3-dimethoxypropionamide (1) in the maximal electroshock (MES)-induced seizure test in mice was 30 mg/kg (Choi, D.; Stables, J.P., Kohn, H. Bioorg. Med. Chem. 1996, 4, 2105). This value is comparable to that observ …
We recently reported that the ED50 value for (R,S)-2,3-dimethoxypropionamide (1) in the maximal electroshock (MES)-induced seizure test in m …
Functionalized amido ketones: new anticonvulsant agents.
Béguin C, Andurkar SV, Jin AY, Stables JP, Weaver DF, Kohn H. Béguin C, et al. Among authors: kohn h. Bioorg Med Chem. 2003 Sep 15;11(19):4275-85. doi: 10.1016/s0968-0896(03)00434-6. Bioorg Med Chem. 2003. PMID: 12951158
Chimeric agents derived from the functionalized amino acid, lacosamide, and the α-aminoamide, safinamide: evaluation of their inhibitory actions on voltage-gated sodium channels, and antiseizure and antinociception activities and comparison with lacosamide and safinamide.
Park KD, Yang XF, Dustrude ET, Wang Y, Ripsch MS, White FA, Khanna R, Kohn H. Park KD, et al. Among authors: kohn h. ACS Chem Neurosci. 2015 Feb 18;6(2):316-30. doi: 10.1021/cn5002182. Epub 2014 Dec 9. ACS Chem Neurosci. 2015. PMID: 25418676 Free PMC article.
345 results