Watson IA - Search Results

1

Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis.

Conrado DJ, Nicholas T, Tsai K, Macha S, Sinha V, Stone J, Corrigan B, Bani M, Muglia P, Watson IA, Kern VD, Sheveleva E, Marek K, Stephenson DT, Romero K; Critical Path for Parkinson's (CPP) Parkinson's Disease Modeling and Simulation Working Group. Conrado DJ, et al. Among authors: watson ia. Clin Transl Sci. 2018 Jan;11(1):63-70. doi: 10.1111/cts.12492. Epub 2017 Jul 27. Clin Transl Sci. 2018. PMID: 28749580 Free PMC article.

2

Clinical and cost implications of amyloid beta detection with amyloid beta positron emission tomography imaging in early Alzheimer's disease - the case of florbetapir.

Hornberger J, Bae J, Watson I, Johnston J, Happich M. Hornberger J, et al. Curr Med Res Opin. 2017 Apr;33(4):675-685. doi: 10.1080/03007995.2016.1277197. Epub 2017 Jan 24. Curr Med Res Opin. 2017. PMID: 28035842

3

Drug wastage and costs to the healthcare system in the care of patients with non-small cell lung cancer in the United States.

Hess LM, Cui ZL, Li XI, Oton AB, Shortenhaus S, Watson IA. Hess LM, et al. Among authors: watson ia. J Med Econ. 2018 Aug;21(8):755-761. doi: 10.1080/13696998.2018.1467918. Epub 2018 May 11. J Med Econ. 2018. PMID: 29673274 Free article.

4

Dissimilarity-based approaches to compound acquisition.

Lajiness M, Watson I. Lajiness M, et al. Curr Opin Chem Biol. 2008 Jun;12(3):366-71. doi: 10.1016/j.cbpa.2008.03.010. Epub 2008 May 28. Curr Opin Chem Biol. 2008. PMID: 18423415 Review.

5

Open Innovation Drug Discovery (OIDD): a potential path to novel therapeutic chemical space.

Alvim-Gaston M, Grese T, Mahoui A, Palkowitz AD, Pineiro-Nunez M, Watson I. Alvim-Gaston M, et al. Curr Top Med Chem. 2014;14(3):294-303. doi: 10.2174/1568026613666131127125858. Curr Top Med Chem. 2014. PMID: 24283973 Review.

6

Minimization of olaratumab drug waste using real-world data.

Sheffield KM, Beyrer JK, Watson IA, Stafford K, Mills BJ, Ale-Ali A. Sheffield KM, et al. Among authors: watson ia. Am J Health Syst Pharm. 2017 Jun 1;74(11):832-842. doi: 10.2146/ajhp160254. Epub 2017 May 1. Am J Health Syst Pharm. 2017. PMID: 28461327

7

The Proximal Lilly Collection: Mapping, Exploring and Exploiting Feasible Chemical Space.

Nicolaou CA, Watson IA, Hu H, Wang J. Nicolaou CA, et al. Among authors: watson ia. J Chem Inf Model. 2016 Jul 25;56(7):1253-66. doi: 10.1021/acs.jcim.6b00173. Epub 2016 Jun 27. J Chem Inf Model. 2016. PMID: 27286472

8

Context Aware Data-Driven Retrosynthetic Analysis.

Nicolaou CA, Watson IA, LeMasters M, Masquelin T, Wang J. Nicolaou CA, et al. Among authors: watson ia. J Chem Inf Model. 2020 Jun 22;60(6):2728-2738. doi: 10.1021/acs.jcim.9b01141. Epub 2020 Apr 24. J Chem Inf Model. 2020. PMID: 32282195

9

Rationalizing lead optimization by associating quantitative relevance with molecular structure modification.

Raymond JW, Watson IA, Mahoui A. Raymond JW, et al. Among authors: watson ia. J Chem Inf Model. 2009 Aug;49(8):1952-62. doi: 10.1021/ci9000426. J Chem Inf Model. 2009. PMID: 19603805

10

Indirect similarity based methods for effective scaffold-hopping in chemical compounds.

Wale N, Watson IA, Karypis G. Wale N, et al. Among authors: watson ia. J Chem Inf Model. 2008 Apr;48(4):730-41. doi: 10.1021/ci700369e. Epub 2008 Apr 11. J Chem Inf Model. 2008. PMID: 18402435 Free PMC article.

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