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Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells.
Streicher C, Heyny A, Andrukhova O, Haigl B, Slavic S, Schüler C, Kollmann K, Kantner I, Sexl V, Kleiter M, Hofbauer LC, Kostenuik PJ, Erben RG. Streicher C, et al. Among authors: kostenuik pj. Sci Rep. 2017 Jul 25;7(1):6460. doi: 10.1038/s41598-017-06614-0. Sci Rep. 2017. PMID: 28744019 Free PMC article.
RANKL inhibition with osteoprotegerin increases bone strength by improving cortical and trabecular bone architecture in ovariectomized rats.
Ominsky MS, Li X, Asuncion FJ, Barrero M, Warmington KS, Dwyer D, Stolina M, Geng Z, Grisanti M, Tan HL, Corbin T, McCabe J, Simonet WS, Ke HZ, Kostenuik PJ. Ominsky MS, et al. Among authors: kostenuik pj. J Bone Miner Res. 2008 May;23(5):672-82. doi: 10.1359/jbmr.080109. J Bone Miner Res. 2008. PMID: 18433301 Free article.
Selective inhibition of receptor activator of NF-κB ligand (RANKL) in hematopoietic cells improves outcome after experimental myocardial infarction.
Slavic S, Andrukhova O, Ford K, Handschuh S, Latic N, Reichart U, Sasgary S, Bergow C, Hofbauer LC, Kostenuik PJ, Erben RG. Slavic S, et al. Among authors: kostenuik pj. J Mol Med (Berl). 2018 Jun;96(6):559-573. doi: 10.1007/s00109-018-1641-x. Epub 2018 May 8. J Mol Med (Berl). 2018. PMID: 29736604 Free PMC article.
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism.
Li J, Sarosi I, Yan XQ, Morony S, Capparelli C, Tan HL, McCabe S, Elliott R, Scully S, Van G, Kaufman S, Juan SC, Sun Y, Tarpley J, Martin L, Christensen K, McCabe J, Kostenuik P, Hsu H, Fletcher F, Dunstan CR, Lacey DL, Boyle WJ. Li J, et al. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1566-71. doi: 10.1073/pnas.97.4.1566. Proc Natl Acad Sci U S A. 2000. PMID: 10677500 Free PMC article.
The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.
Morony S, Warmington K, Adamu S, Asuncion F, Geng Z, Grisanti M, Tan HL, Capparelli C, Starnes C, Weimann B, Dunstan CR, Kostenuik PJ. Morony S, et al. Among authors: kostenuik pj. Endocrinology. 2005 Aug;146(8):3235-43. doi: 10.1210/en.2004-1583. Epub 2005 Apr 21. Endocrinology. 2005. PMID: 15845617
121 results