Wyllie DJA - Search Results

1

Pro-death NMDA receptor signaling is promoted by the GluN2B C-terminus independently of Dapk1.

McQueen J, Ryan TJ, McKay S, Marwick K, Baxter P, Carpanini SM, Wishart TM, Gillingwater TH, Manson JC, Wyllie DJA, Grant SGN, McColl BW, Komiyama NH, Hardingham GE. McQueen J, et al. Among authors: wyllie dja. Elife. 2017 Jul 21;6:e17161. doi: 10.7554/eLife.17161. Elife. 2017. PMID: 28731405 Free PMC article.

2

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, Wyllie DJA, O'Dell TJ, Grant SGN, Hardingham GE, Komiyama NH. McKay S, et al. Among authors: wyllie dja. Cell Rep. 2018 Oct 23;25(4):841-851.e4. doi: 10.1016/j.celrep.2018.09.089. Cell Rep. 2018. PMID: 30355491 Free PMC article.

3

Inhibiting pro-death NMDA receptor signaling dependent on the NR2 PDZ ligand may not affect synaptic function or synaptic NMDA receptor signaling to gene expression.

Martel MA, Soriano FX, Baxter P, Rickman C, Duncan R, Wyllie DJ, Hardingham GE. Martel MA, et al. Channels (Austin). 2009 Jan-Feb;3(1):12-5. doi: 10.4161/chan.3.1.7864. Epub 2009 Jan 16. Channels (Austin). 2009. PMID: 19221512

4

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist.

McKay S, Griffiths NH, Butters PA, Thubron EB, Hardingham GE, Wyllie DJ. McKay S, et al. Br J Pharmacol. 2012 Jun;166(3):924-37. doi: 10.1111/j.1476-5381.2011.01748.x. Br J Pharmacol. 2012. PMID: 22022974 Free PMC article.

5

Influence of GluN2 subunit identity on NMDA receptor function.

Wyllie DJ, Livesey MR, Hardingham GE. Wyllie DJ, et al. Neuropharmacology. 2013 Nov;74:4-17. doi: 10.1016/j.neuropharm.2013.01.016. Epub 2013 Jan 31. Neuropharmacology. 2013. PMID: 23376022 Free PMC article. Review.

6

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death.

Martel MA, Wyllie DJ, Hardingham GE. Martel MA, et al. Neuroscience. 2009 Jan 12;158(1):334-43. doi: 10.1016/j.neuroscience.2008.01.080. Epub 2008 Mar 4. Neuroscience. 2009. PMID: 18378405 Free PMC article.

7

Recovery of NMDA receptor currents from MK-801 blockade is accelerated by Mg2+ and memantine under conditions of agonist exposure.

McKay S, Bengtson CP, Bading H, Wyllie DJ, Hardingham GE. McKay S, et al. Neuropharmacology. 2013 Nov;74:119-25. doi: 10.1016/j.neuropharm.2013.01.024. Epub 2013 Feb 10. Neuropharmacology. 2013. PMID: 23402996 Free PMC article.

8

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons.

Qiu J, McQueen J, Bilican B, Dando O, Magnani D, Punovuori K, Selvaraj BT, Livesey M, Haghi G, Heron S, Burr K, Patani R, Rajan R, Sheppard O, Kind PC, Simpson TI, Tybulewicz VL, Wyllie DJ, Fisher EM, Lowell S, Chandran S, Hardingham GE. Qiu J, et al. Elife. 2016 Oct 1;5:e20337. doi: 10.7554/eLife.20337. Elife. 2016. PMID: 27692071 Free PMC article.

9

Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy.

Marwick KFM, Hansen KB, Skehel PA, Hardingham GE, Wyllie DJA. Marwick KFM, et al. Among authors: wyllie dja. J Physiol. 2019 Mar;597(6):1691-1704. doi: 10.1113/JP277292. Epub 2019 Jan 30. J Physiol. 2019. PMID: 30604514 Free PMC article.

10

The human NMDA receptor GluN2A^N615K variant influences channel blocker potency.

Marwick KFM, Skehel PA, Hardingham GE, Wyllie DJA. Marwick KFM, et al. Among authors: wyllie dja. Pharmacol Res Perspect. 2019 Jun 20;7(4):e00495. doi: 10.1002/prp2.495. eCollection 2019 Aug. Pharmacol Res Perspect. 2019. PMID: 31249692 Free PMC article.

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