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Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia.
Chorzalska A, Kim JF, Roder K, Tepper A, Ahsan N, Rao RSP, Olszewski AJ, Yu X, Terentyev D, Morgan J, Treaba DO, Zhao TC, Liang O, Gruppuso PA, Dubielecka PM. Chorzalska A, et al. Among authors: dubielecka pm. Stem Cells Dev. 2017 May 1;26(9):656-677. doi: 10.1089/scd.2016.0262. Epub 2017 Feb 27. Stem Cells Dev. 2017. PMID: 28103766 Free PMC article.
Overexpression of Tpl2 is linked to imatinib resistance and activation of MEK-ERK and NF-κB pathways in a model of chronic myeloid leukemia.
Chorzalska A, Ahsan N, Rao RSP, Roder K, Yu X, Morgan J, Tepper A, Hines S, Zhang P, Treaba DO, Zhao TC, Olszewski AJ, Reagan JL, Liang O, Gruppuso PA, Dubielecka PM. Chorzalska A, et al. Among authors: dubielecka pm. Mol Oncol. 2018 May;12(5):630-647. doi: 10.1002/1878-0261.12186. Epub 2018 Apr 6. Mol Oncol. 2018. PMID: 29485707 Free PMC article.
Bone marrow-specific loss of ABI1 induces myeloproliferative neoplasm with features resembling human myelofibrosis.
Chorzalska A, Morgan J, Ahsan N, Treaba DO, Olszewski AJ, Petersen M, Kingston N, Cheng Y, Lombardo K, Schorl C, Yu X, Zini R, Pacilli A, Tepper A, Coburn J, Hryniewicz-Jankowska A, Zhao TC, Oancea E, Reagan JL, Liang O, Kotula L, Quesenberry PJ, Gruppuso PA, Manfredini R, Vannucchi AM, Dubielecka PM. Chorzalska A, et al. Among authors: dubielecka pm. Blood. 2018 Nov 8;132(19):2053-2066. doi: 10.1182/blood-2018-05-848408. Epub 2018 Sep 13. Blood. 2018. PMID: 30213875 Free PMC article.
Targeting RUNX1 as a novel treatment modality for pulmonary arterial hypertension.
Jeong EM, Pereira M, So EY, Wu KQ, Del Tatto M, Wen S, Dooner MS, Dubielecka PM, Reginato AM, Ventetuolo CE, Quesenberry PJ, Klinger JR, Liang OD. Jeong EM, et al. Among authors: dubielecka pm. Cardiovasc Res. 2022 Dec 29;118(16):3211-3224. doi: 10.1093/cvr/cvac001. Cardiovasc Res. 2022. PMID: 35018410 Free PMC article.
Transcriptomics of acute myeloid leukaemia core bone marrow biopsies reveals distinct therapy response-specific osteo-mesenchymal profiles.
Treaba DO, Bonal DM, Chorzalska A, Castillo-Martin M, Oakes A, Pardo M, Petersen M, Schorl C, Hopkins K, Melcher D, Zhao TC, Liang O, So EY, Reagan J, Olszewski AJ, Butera J, Anthony DC, Rintels P, Quesenberry P, Dubielecka PM. Treaba DO, et al. Among authors: dubielecka pm. Br J Haematol. 2023 Mar;200(6):740-754. doi: 10.1111/bjh.18513. Epub 2022 Nov 10. Br J Haematol. 2023. PMID: 36354085
57 results