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Development of Phosphorothioate DNA and DNA Thioaptamers.
Volk DE, Lokesh GLR. Volk DE, et al. Among authors: lokesh glr. Biomedicines. 2017 Jul 13;5(3):41. doi: 10.3390/biomedicines5030041. Biomedicines. 2017. PMID: 28703779 Free PMC article. Review.
Thioaptamers targeting dengue virus type-2 envelope protein domain III.
Gandham SH, Volk DE, Lokesh GL, Neerathilingam M, Gorenstein DG. Gandham SH, et al. Biochem Biophys Res Commun. 2014 Oct 24;453(3):309-15. doi: 10.1016/j.bbrc.2014.09.053. Epub 2014 Sep 26. Biochem Biophys Res Commun. 2014. PMID: 25261724 Free PMC article.
Therapeutic Targeting of AXL Receptor Tyrosine Kinase Inhibits Tumor Growth and Intraperitoneal Metastasis in Ovarian Cancer Models.
Kanlikilicer P, Ozpolat B, Aslan B, Bayraktar R, Gurbuz N, Rodriguez-Aguayo C, Bayraktar E, Denizli M, Gonzalez-Villasana V, Ivan C, Lokesh GLR, Amero P, Catuogno S, Haemmerle M, Wu SY, Mitra R, Gorenstein DG, Volk DE, de Franciscis V, Sood AK, Lopez-Berestein G. Kanlikilicer P, et al. Among authors: lokesh glr. Mol Ther Nucleic Acids. 2017 Dec 15;9:251-262. doi: 10.1016/j.omtn.2017.06.023. Epub 2017 Jul 5. Mol Ther Nucleic Acids. 2017. PMID: 29246304 Free PMC article.
Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity.
Amero P, Lokesh GLR, Chaudhari RR, Cardenas-Zuniga R, Schubert T, Attia YM, Montalvo-Gonzalez E, Elsayed AM, Ivan C, Wang Z, Cristini V, Franciscis V, Zhang S, Volk DE, Mitra R, Rodriguez-Aguayo C, Sood AK, Lopez-Berestein G. Amero P, et al. Among authors: lokesh glr. J Am Chem Soc. 2021 May 26;143(20):7655-7670. doi: 10.1021/jacs.9b10460. Epub 2021 May 14. J Am Chem Soc. 2021. PMID: 33988982
X-Aptamer Selection and Validation.
Lokesh GL, Wang H, Lam CH, Thiviyanathan V, Ward N, Gorenstein DG, Volk DE. Lokesh GL, et al. Methods Mol Biol. 2017;1632:151-174. doi: 10.1007/978-1-4939-7138-1_10. Methods Mol Biol. 2017. PMID: 28730438
22 results