O'Carroll D - Search Results

1

The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses.

Kozlowski E, Wasserman GA, Morgan M, O'Carroll D, Ramirez NP, Gummuluru S, Rah JY, Gower AC, Ieong M, Quinton LJ, Mizgerd JP, Jones MR. Kozlowski E, et al. PLoS One. 2017 Jun 30;12(6):e0179797. doi: 10.1371/journal.pone.0179797. eCollection 2017. PLoS One. 2017. PMID: 28665939 Free PMC article.

2

Multiple epigenetic mechanisms and the piRNA pathway enforce LINE1 silencing during adult spermatogenesis.

Di Giacomo M, Comazzetto S, Saini H, De Fazio S, Carrieri C, Morgan M, Vasiliauskaite L, Benes V, Enright AJ, O'Carroll D. Di Giacomo M, et al. Mol Cell. 2013 May 23;50(4):601-8. doi: 10.1016/j.molcel.2013.04.026. Mol Cell. 2013. PMID: 23706823 Free article.

3

Oligoasthenoteratozoospermia and infertility in mice deficient for miR-34b/c and miR-449 loci.

Comazzetto S, Di Giacomo M, Rasmussen KD, Much C, Azzi C, Perlas E, Morgan M, O'Carroll D. Comazzetto S, et al. PLoS Genet. 2014 Oct 16;10(10):e1004597. doi: 10.1371/journal.pgen.1004597. eCollection 2014 Oct. PLoS Genet. 2014. PMID: 25329700 Free PMC article.

4

A transit-amplifying population underpins the efficient regenerative capacity of the testis.

Carrieri C, Comazzetto S, Grover A, Morgan M, Buness A, Nerlov C, O'Carroll D. Carrieri C, et al. J Exp Med. 2017 Jun 5;214(6):1631-1641. doi: 10.1084/jem.20161371. Epub 2017 May 1. J Exp Med. 2017. PMID: 28461596 Free PMC article.

5

mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome.

Morgan M, Much C, DiGiacomo M, Azzi C, Ivanova I, Vitsios DM, Pistolic J, Collier P, Moreira PN, Benes V, Enright AJ, O'Carroll D. Morgan M, et al. Nature. 2017 Aug 17;548(7667):347-351. doi: 10.1038/nature23318. Epub 2017 Aug 9. Nature. 2017. PMID: 28792939 Free PMC article.

6

The RNA m⁶A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence.

Ivanova I, Much C, Di Giacomo M, Azzi C, Morgan M, Moreira PN, Monahan J, Carrieri C, Enright AJ, O'Carroll D. Ivanova I, et al. Mol Cell. 2017 Sep 21;67(6):1059-1067.e4. doi: 10.1016/j.molcel.2017.08.003. Epub 2017 Aug 31. Mol Cell. 2017. PMID: 28867294 Free PMC article.

7

Expression of Piwi protein MIWI2 defines a distinct population of multiciliated cells.

Wasserman GA, Szymaniak AD, Hinds AC, Yamamoto K, Kamata H, Smith NM, Hilliard KL, Carrieri C, Labadorf AT, Quinton LJ, Ai X, Varelas X, Chen F, Mizgerd JP, Fine A, O'Carroll D, Jones MR. Wasserman GA, et al. J Clin Invest. 2017 Oct 2;127(10):3866-3876. doi: 10.1172/JCI94639. Epub 2017 Sep 18. J Clin Invest. 2017. PMID: 28920925 Free PMC article.

8

Terminal uridylyltransferases target RNA viruses as part of the innate immune system.

Le Pen J, Jiang H, Di Domenico T, Kneuss E, Kosałka J, Leung C, Morgan M, Much C, Rudolph KLM, Enright AJ, O'Carroll D, Wang D, Miska EA. Le Pen J, et al. Nat Struct Mol Biol. 2018 Sep;25(9):778-786. doi: 10.1038/s41594-018-0106-9. Epub 2018 Aug 13. Nat Struct Mol Biol. 2018. PMID: 30104661 Free PMC article.

9

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.

Morgan M, Kabayama Y, Much C, Ivanova I, Di Giacomo M, Auchynnikava T, Monahan JM, Vitsios DM, Vasiliauskaitė L, Comazzetto S, Rappsilber J, Allshire RC, Porse BT, Enright AJ, O'Carroll D. Morgan M, et al. Cell Res. 2019 Mar;29(3):221-232. doi: 10.1038/s41422-018-0128-1. Epub 2019 Jan 7. Cell Res. 2019. PMID: 30617251 Free PMC article.

10

Targeting the RNA m⁶A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia.

Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, Villacreces A, Much C, Choe J, Azar A, van de Lagemaat LN, Vernimmen D, Nehme A, Mazurier F, Somervaille TCP, Gregory RI, O'Carroll D, Kranc KR. Paris J, et al. Cell Stem Cell. 2019 Jul 3;25(1):137-148.e6. doi: 10.1016/j.stem.2019.03.021. Epub 2019 Apr 25. Cell Stem Cell. 2019. PMID: 31031138 Free PMC article.

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