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Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins.
Yang NJ, Kauke MJ, Sun F, Yang LF, Maass KF, Traxlmayr MW, Yu Y, Xu Y, Langer RS, Anderson DG, Wittrup KD. Yang NJ, et al. Among authors: traxlmayr mw. Nucleic Acids Res. 2017 Jul 27;45(13):7602-7614. doi: 10.1093/nar/gkx546. Nucleic Acids Res. 2017. PMID: 28641400 Free PMC article.
An engineered protein antagonist of K-Ras/B-Raf interaction.
Kauke MJ, Traxlmayr MW, Parker JA, Kiefer JD, Knihtila R, McGee J, Verdine G, Mattos C, Wittrup KD. Kauke MJ, et al. Among authors: traxlmayr mw. Sci Rep. 2017 Jul 19;7(1):5831. doi: 10.1038/s41598-017-05889-7. Sci Rep. 2017. PMID: 28724936 Free PMC article.
Protein Engineering and Selection Using Yeast Surface Display.
Angelini A, Chen TF, de Picciotto S, Yang NJ, Tzeng A, Santos MS, Van Deventer JA, Traxlmayr MW, Wittrup KD. Angelini A, et al. Among authors: traxlmayr mw. Methods Mol Biol. 2015;1319:3-36. doi: 10.1007/978-1-4939-2748-7_1. Methods Mol Biol. 2015. PMID: 26060067
Design Principles for SuCESsFul Biosensors: Specific Fluorophore/Analyte Binding and Minimization of Fluorophore/Scaffold Interactions.
de Picciotto S, Dickson PM, Traxlmayr MW, Marques BS, Socher E, Zhao S, Cheung S, Kiefer JD, Wand AJ, Griffith LG, Imperiali B, Wittrup KD. de Picciotto S, et al. Among authors: traxlmayr mw. J Mol Biol. 2016 Oct 9;428(20):4228-4241. doi: 10.1016/j.jmb.2016.07.004. Epub 2016 Jul 21. J Mol Biol. 2016. PMID: 27448945 Free PMC article.
A conformation-specific ON-switch for controlling CAR T cells with an orally available drug.
Zajc CU, Dobersberger M, Schaffner I, Mlynek G, Pühringer D, Salzer B, Djinović-Carugo K, Steinberger P, De Sousa Linhares A, Yang NJ, Obinger C, Holter W, Traxlmayr MW, Lehner M. Zajc CU, et al. Among authors: traxlmayr mw. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):14926-14935. doi: 10.1073/pnas.1911154117. Epub 2020 Jun 17. Proc Natl Acad Sci U S A. 2020. PMID: 32554495 Free PMC article.
Engineered IgG1-Fc--one fragment to bind them all.
Lobner E, Traxlmayr MW, Obinger C, Hasenhindl C. Lobner E, et al. Among authors: traxlmayr mw. Immunol Rev. 2016 Mar;270(1):113-31. doi: 10.1111/imr.12385. Immunol Rev. 2016. PMID: 26864108 Free PMC article. Review.
31 results