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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
López-Iglesias AA, Herrero AB, Chesi M, San-Segundo L, González-Méndez L, Hernández-García S, Misiewicz-Krzeminska I, Quwaider D, Martín-Sánchez M, Primo D, Paíno T, Bergsagel PL, Mehrling T, González-Díaz M, San-Miguel JF, Mateos MV, Gutiérrez NC, Garayoa M, Ocio EM. López-Iglesias AA, et al. J Hematol Oncol. 2017 Jun 20;10(1):127. doi: 10.1186/s13045-017-0495-y. J Hematol Oncol. 2017. PMID: 28633670 Free PMC article.
The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Hernández-García S, San-Segundo L, González-Méndez L, Corchete LA, Misiewicz-Krzeminska I, Martín-Sánchez M, López-Iglesias AA, Algarín EM, Mogollón P, Díaz-Tejedor A, Paíno T, Tunquist B, Mateos MV, Gutiérrez NC, Díaz-Rodriguez E, Garayoa M, Ocio EM. Hernández-García S, et al. Haematologica. 2017 Dec;102(12):2113-2124. doi: 10.3324/haematol.2017.168666. Epub 2017 Aug 31. Haematologica. 2017. PMID: 28860344 Free PMC article.
Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma.
Rojas EA, Corchete LA, San-Segundo L, Martínez-Blanch JF, Codoñer FM, Paíno T, Puig N, García-Sanz R, Mateos MV, Ocio EM, Misiewicz-Krzeminska I, Gutiérrez NC. Rojas EA, et al. Clin Cancer Res. 2017 Nov 1;23(21):6602-6615. doi: 10.1158/1078-0432.CCR-17-0678. Epub 2017 Aug 8. Clin Cancer Res. 2017. PMID: 28790111
Expression of p53 protein isoforms predicts survival in patients with multiple myeloma.
Rojas EA, Corchete LA, De Ramón C, Krzeminski P, Quwaider D, García-Sanz R, Martínez-López J, Oriol A, Rosiñol L, Bladé J, Lahuerta JJ, San Miguel JF, González M, Mateos MV, Bourdon JC, Misiewicz-Krzeminska I, Gutiérrez NC. Rojas EA, et al. Among authors: misiewicz krzeminska i. Am J Hematol. 2022 Jun 1;97(6):700-710. doi: 10.1002/ajh.26507. Epub 2022 Mar 1. Am J Hematol. 2022. PMID: 35188691 Free PMC article. Clinical Trial.
Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication.
Misiewicz-Krzeminska I, Sarasquete ME, Quwaider D, Krzeminski P, Ticona FV, Paíno T, Delgado M, Aires A, Ocio EM, García-Sanz R, San Miguel JF, Gutiérrez NC. Misiewicz-Krzeminska I, et al. Haematologica. 2013 Apr;98(4):640-8. doi: 10.3324/haematol.2012.070011. Epub 2012 Oct 25. Haematologica. 2013. PMID: 23100276 Free PMC article.
Insights into epigenetic regulation of microRNA-155 expression in multiple myeloma.
Krzeminski P, Sarasquete ME, Misiewicz-Krzeminska I, Corral R, Corchete LA, Martín AA, García-Sanz R, San Miguel JF, Gutiérrez NC. Krzeminski P, et al. Biochim Biophys Acta. 2015 Mar;1849(3):353-66. doi: 10.1016/j.bbagrm.2014.12.002. Epub 2014 Dec 11. Biochim Biophys Acta. 2015. PMID: 25497370
Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma.
Misiewicz-Krzeminska I, Sarasquete ME, Vicente-Dueñas C, Krzeminski P, Wiktorska K, Corchete LA, Quwaider D, Rojas EA, Corral R, Martín AA, Escalante F, Bárez A, García JL, Sánchez-García I, García-Sanz R, San Miguel JF, Gutiérrez NC. Misiewicz-Krzeminska I, et al. Clin Cancer Res. 2016 Jan 1;22(1):207-17. doi: 10.1158/1078-0432.CCR-14-2796. Epub 2015 Sep 4. Clin Cancer Res. 2016. PMID: 26341922
A novel nano-immunoassay method for quantification of proteins from CD138-purified myeloma cells: biological and clinical utility.
Misiewicz-Krzeminska I, Corchete LA, Rojas EA, Martínez-López J, García-Sanz R, Oriol A, Bladé J, Lahuerta JJ, Miguel JS, Mateos MV, Gutiérrez NC. Misiewicz-Krzeminska I, et al. Haematologica. 2018 May;103(5):880-889. doi: 10.3324/haematol.2017.181628. Epub 2018 Mar 15. Haematologica. 2018. PMID: 29545347 Free PMC article.
36 results