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Preclinical anti-myeloma activity of EDO-S101, a new bendamustine-derived molecule with added HDACi activity, through potent DNA damage induction and impairment of DNA repair.
López-Iglesias AA, Herrero AB, Chesi M, San-Segundo L, González-Méndez L, Hernández-García S, Misiewicz-Krzeminska I, Quwaider D, Martín-Sánchez M, Primo D, Paíno T, Bergsagel PL, Mehrling T, González-Díaz M, San-Miguel JF, Mateos MV, Gutiérrez NC, Garayoa M, Ocio EM. López-Iglesias AA, et al. Among authors: bergsagel pl. J Hematol Oncol. 2017 Jun 20;10(1):127. doi: 10.1186/s13045-017-0495-y. J Hematol Oncol. 2017. PMID: 28633670 Free PMC article.
Dysregulation of c-myc in multiple myeloma.
Kuehl WM, Brents LA, Chesi M, Huppi K, Bergsagel PL. Kuehl WM, et al. Among authors: bergsagel pl. Curr Top Microbiol Immunol. 1997;224:277-82. doi: 10.1007/978-3-642-60801-8_29. Curr Top Microbiol Immunol. 1997. PMID: 9308252
Bone lesions in molecular subtypes of multiple myeloma.
Robbiani DF, Chesi M, Bergsagel PL. Robbiani DF, et al. Among authors: bergsagel pl. N Engl J Med. 2004 Jul 8;351(2):197-8. doi: 10.1056/NEJM200407083510223. N Engl J Med. 2004. PMID: 15247367 No abstract available.
Ploidy status rarely changes in myeloma patients at disease progression.
Chng WJ, Winkler JM, Greipp PR, Jalal SM, Bergsagel PL, Chesi M, Trendle MC, Ahmann GJ, Henderson K, Blood E, Oken MM, Hulbert A, Van Wier SA, Santana-Dávila R, Kyle RA, Gertz MA, Lacy MQ, Dispenzieri A, Fonseca R. Chng WJ, et al. Among authors: bergsagel pl. Leuk Res. 2006 Mar;30(3):266-71. doi: 10.1016/j.leukres.2005.07.004. Epub 2005 Aug 18. Leuk Res. 2006. PMID: 16111750 Clinical Trial.
Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.
Keats JJ, Fonseca R, Chesi M, Schop R, Baker A, Chng WJ, Van Wier S, Tiedemann R, Shi CX, Sebag M, Braggio E, Henry T, Zhu YX, Fogle H, Price-Troska T, Ahmann G, Mancini C, Brents LA, Kumar S, Greipp P, Dispenzieri A, Bryant B, Mulligan G, Bruhn L, Barrett M, Valdez R, Trent J, Stewart AK, Carpten J, Bergsagel PL. Keats JJ, et al. Among authors: bergsagel pl. Cancer Cell. 2007 Aug;12(2):131-44. doi: 10.1016/j.ccr.2007.07.003. Cancer Cell. 2007. PMID: 17692805 Free PMC article.
257 results