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Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.
Toba S, Tamura Y, Kumamoto K, Yamada M, Takao K, Hattori S, Miyakawa T, Kataoka Y, Azuma M, Hayasaka K, Amamoto M, Tominaga K, Wynshaw-Boris A, Wanibuchi H, Oka Y, Sato M, Kato M, Hirotsune S. Toba S, et al. Among authors: sato m. Sci Rep. 2013;3:1224. doi: 10.1038/srep01224. Epub 2013 Feb 6. Sci Rep. 2013. PMID: 23390575 Free PMC article.
DBZ regulates cortical cell positioning and neurite development by sustaining the anterograde transport of Lis1 and DISC1 through control of Ndel1 dual-phosphorylation.
Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M. Okamoto M, et al. Among authors: sato m. J Neurosci. 2015 Feb 18;35(7):2942-58. doi: 10.1523/JNEUROSCI.5029-13.2015. J Neurosci. 2015. PMID: 25698733 Free PMC article.
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