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The Novel Anticancer Drug Hydroxytriolein Inhibits Lung Cancer Cell Proliferation via a Protein Kinase Cα- and Extracellular Signal-Regulated Kinase 1/2-Dependent Mechanism.
Guardiola-Serrano F, Beteta-Göbel R, Rodríguez-Lorca R, Ibarguren M, López DJ, Terés S, Alvarez R, Alonso-Sande M, Busquets X, Escribá PV. Guardiola-Serrano F, et al. J Pharmacol Exp Ther. 2015 Aug;354(2):213-24. doi: 10.1124/jpet.114.222281. Epub 2015 Jun 11. J Pharmacol Exp Ther. 2015. PMID: 26065701
Role of the C-terminal basic amino acids and the lipid anchor of the Gγ2 protein in membrane interactions and cell localization.
Noguera-Salvà MA, Guardiola-Serrano F, Martin ML, Marcilla-Etxenike A, Bergo MO, Busquets X, Escribá PV. Noguera-Salvà MA, et al. Among authors: guardiola serrano f. Biochim Biophys Acta Biomembr. 2017 Sep;1859(9 Pt B):1536-1547. doi: 10.1016/j.bbamem.2017.02.012. Epub 2017 Feb 21. Biochim Biophys Acta Biomembr. 2017. PMID: 28235469 Free article.
The triacylglycerol, hydroxytriolein, inhibits triple negative mammary breast cancer cell proliferation through a mechanism dependent on dihydroceramide and Akt.
Guardiola-Serrano F, Beteta-Göbel R, Rodríguez-Lorca R, Ibarguren M, López DJ, Terés S, Alonso-Sande M, Higuera M, Torres M, Busquets X, Escribá PV. Guardiola-Serrano F, et al. Oncotarget. 2019 Apr 2;10(26):2486-2507. doi: 10.18632/oncotarget.26824. eCollection 2019 Apr 2. Oncotarget. 2019. PMID: 31069012 Free PMC article.
Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets.
Piotto S, Concilio S, Bianchino E, Iannelli P, López DJ, Terés S, Ibarguren M, Barceló-Coblijn G, Martin ML, Guardiola-Serrano F, Alonso-Sande M, Funari SS, Busquets X, Escribá PV. Piotto S, et al. Among authors: guardiola serrano f. Biochim Biophys Acta. 2014 Jun;1838(6):1628-37. doi: 10.1016/j.bbamem.2013.12.023. Epub 2014 Jan 9. Biochim Biophys Acta. 2014. PMID: 24412218 Free article.
Sphingomyelin and sphingomyelin synthase (SMS) in the malignant transformation of glioma cells and in 2-hydroxyoleic acid therapy.
Barceló-Coblijn G, Martin ML, de Almeida RF, Noguera-Salvà MA, Marcilla-Etxenike A, Guardiola-Serrano F, Lüth A, Kleuser B, Halver JE, Escribá PV. Barceló-Coblijn G, et al. Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19569-74. doi: 10.1073/pnas.1115484108. Epub 2011 Nov 21. Proc Natl Acad Sci U S A. 2011. PMID: 22106271 Free PMC article.
Identification of Biomarkers of Necrosis in Xenografts Using Imaging Mass Spectrometry.
Fernández R, Garate J, Lage S, Terés S, Higuera M, Bestard-Escalas J, López DH, Guardiola-Serrano F, Escribá PV, Barceló-Coblijn G, Fernández JA. Fernández R, et al. Among authors: guardiola serrano f. J Am Soc Mass Spectrom. 2016 Feb;27(2):244-54. doi: 10.1007/s13361-015-1268-x. Epub 2015 Sep 25. J Am Soc Mass Spectrom. 2016. PMID: 26407555
Optimized Protocol To Analyze Changes in the Lipidome of Xenografts after Treatment with 2-Hydroxyoleic Acid.
Fernández R, Garate J, Lage S, Terés S, Higuera M, Bestard-Escalas J, Martin ML, López DH, Guardiola-Serrano F, Escribá PV, Barceló-Coblijn G, Fernández JA. Fernández R, et al. Among authors: guardiola serrano f. Anal Chem. 2016 Jan 5;88(1):1022-9. doi: 10.1021/acs.analchem.5b03978. Epub 2015 Dec 15. Anal Chem. 2016. PMID: 26607740 Free PMC article.
Analysis of the lipidome of xenografts using MALDI-IMS and UHPLC-ESI-QTOF.
Fernández R, Lage S, Abad-García B, Barceló-Coblijn G, Terés S, López DH, Guardiola-Serrano F, Martín ML, Escribá PV, Fernández JA. Fernández R, et al. Among authors: guardiola serrano f. J Am Soc Mass Spectrom. 2014 Jul;25(7):1237-46. doi: 10.1007/s13361-014-0882-3. Epub 2014 Apr 24. J Am Soc Mass Spectrom. 2014. PMID: 24760294
Common and Differential Traits of the Membrane Lipidome of Colon Cancer Cell Lines and their Secreted Vesicles: Impact on Studies Using Cell Lines.
Bestard-Escalas J, Maimó-Barceló A, Lopez DH, Reigada R, Guardiola-Serrano F, Ramos-Vivas J, Hornemann T, Okazaki T, Barceló-Coblijn G. Bestard-Escalas J, et al. Among authors: guardiola serrano f. Cancers (Basel). 2020 May 20;12(5):1293. doi: 10.3390/cancers12051293. Cancers (Basel). 2020. PMID: 32443825 Free PMC article.
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