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High-speed fixed-target serial virus crystallography.
Roedig P, Ginn HM, Pakendorf T, Sutton G, Harlos K, Walter TS, Meyer J, Fischer P, Duman R, Vartiainen I, Reime B, Warmer M, Brewster AS, Young ID, Michels-Clark T, Sauter NK, Kotecha A, Kelly J, Rowlands DJ, Sikorsky M, Nelson S, Damiani DS, Alonso-Mori R, Ren J, Fry EE, David C, Stuart DI, Wagner A, Meents A. Roedig P, et al. Among authors: kelly j. Nat Methods. 2017 Aug;14(8):805-810. doi: 10.1038/nmeth.4335. Epub 2017 Jun 19. Nat Methods. 2017. PMID: 28628129 Free PMC article.
More-powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules.
De Colibus L, Wang X, Spyrou JAB, Kelly J, Ren J, Grimes J, Puerstinger G, Stonehouse N, Walter TS, Hu Z, Wang J, Li X, Peng W, Rowlands D, Fry EE, Rao Z, Stuart DI. De Colibus L, et al. Among authors: kelly j. Nat Struct Mol Biol. 2014 Mar;21(3):282-288. doi: 10.1038/nsmb.2769. Epub 2014 Feb 9. Nat Struct Mol Biol. 2014. PMID: 24509833 Free PMC article.
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Jiang A, You L, Handley RR, Hawkins V, Reid SJ, Jacobsen JC, Patassini S, Rudiger SR, Mclaughlan CJ, Kelly JM, Verma PJ, Bawden CS, Gusella JF, MacDonald ME, Waldvogel HJ, Faull RLM, Lehnert K, Snell RG. Jiang A, et al. Among authors: kelly jm. Hum Mol Genet. 2024 May 22:ddae087. doi: 10.1093/hmg/ddae087. Online ahead of print. Hum Mol Genet. 2024. PMID: 38776957
7,570 results