Amato G - Search Results

1

Discovery of a Series of Indazole TRPA1 Antagonists.

Pryde DC, Marron BE, West CW, Reister S, Amato G, Yoger K, Antonio B, Padilla K, Cox PJ, Turner J, Warmus JS, Swain NA, Omoto K, Mahoney JH, Gerlach AC. Pryde DC, et al. Among authors: amato g. ACS Med Chem Lett. 2017 May 18;8(6):666-671. doi: 10.1021/acsmedchemlett.7b00140. eCollection 2017 Jun 8. ACS Med Chem Lett. 2017. PMID: 28626530 Free PMC article.

2

N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy.

Amato G, Roeloffs R, Rigdon GC, Antonio B, Mersch T, McNaughton-Smith G, Wickenden AD, Fritch P, Suto MJ. Amato G, et al. ACS Med Chem Lett. 2011 Mar 31;2(6):481-4. doi: 10.1021/ml200053x. eCollection 2011 Jun 9. ACS Med Chem Lett. 2011. PMID: 24900334 Free PMC article.

3

Novel KCNQ2/Q3 agonists as potential therapeutics for epilepsy and neuropathic pain.

Fritch PC, McNaughton-Smith G, Amato GS, Burns JF, Eargle CW, Roeloffs R, Harrison W, Jones L, Wickenden AD. Fritch PC, et al. Among authors: amato gs. J Med Chem. 2010 Jan 28;53(2):887-96. doi: 10.1021/jm901497b. J Med Chem. 2010. PMID: 20020710

4

Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.

Amato GS, Manke A, Harris DL, Wiethe RW, Vasukuttan V, Snyder RW, Lefever TW, Cortes R, Zhang Y, Wang S, Runyon SP, Maitra R. Amato GS, et al. J Med Chem. 2018 May 24;61(10):4370-4385. doi: 10.1021/acs.jmedchem.7b01820. Epub 2018 May 10. J Med Chem. 2018. PMID: 29688015 Free PMC article.

5

Functionalized 6-(Piperidin-1-yl)-8,9-Diphenyl Purines as Peripherally Restricted Inverse Agonists of the CB1 Receptor.

Amato G, Manke A, Wiethe R, Vasukuttan V, Snyder R, Yueh YL, Decker A, Runyon S, Maitra R. Amato G, et al. J Med Chem. 2019 Jul 11;62(13):6330-6345. doi: 10.1021/acs.jmedchem.9b00727. Epub 2019 Jun 22. J Med Chem. 2019. PMID: 31185168 Free PMC article.

6

Methyl mercapturate episulfonium ion: a model reactive metabolite of dihaloethanes.

Henkel JG, Amato GS. Henkel JG, et al. Among authors: amato gs. J Med Chem. 1988 Jul;31(7):1279-82. doi: 10.1021/jm00402a003. J Med Chem. 1988. PMID: 3385721 No abstract available.

7

Pyrazole antagonists of the CB1 receptor with reduced brain penetration.

Fulp A, Zhang Y, Bortoff K, Seltzman H, Snyder R, Wiethe R, Amato G, Maitra R. Fulp A, et al. Among authors: amato g. Bioorg Med Chem. 2016 Mar 1;24(5):1063-70. doi: 10.1016/j.bmc.2016.01.033. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827137 Free PMC article.

8

Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel.

Gross MF, Beaudoin S, McNaughton-Smith G, Amato GS, Castle NA, Huang C, Zou A, Yu W. Gross MF, et al. Among authors: amato gs. Bioorg Med Chem Lett. 2007 May 15;17(10):2849-53. doi: 10.1016/j.bmcl.2007.02.052. Epub 2007 Feb 27. Bioorg Med Chem Lett. 2007. PMID: 17350840

9

A patent update on cannabinoid receptor 1 antagonists (2015-2018).

Amato G, Khan NS, Maitra R. Amato G, et al. Expert Opin Ther Pat. 2019 Apr;29(4):261-269. doi: 10.1080/13543776.2019.1597851. Epub 2019 Apr 8. Expert Opin Ther Pat. 2019. PMID: 30889997 Free PMC article. Review.

10

Peripherally Selective CB1 Receptor Antagonist Improves Symptoms of Metabolic Syndrome in Mice.

Khan N, Laudermilk L, Ware J, Rosa T, Mathews K, Gay E, Amato G, Maitra R. Khan N, et al. Among authors: amato g. ACS Pharmacol Transl Sci. 2021 Mar 9;4(2):757-764. doi: 10.1021/acsptsci.0c00213. eCollection 2021 Apr 9. ACS Pharmacol Transl Sci. 2021. PMID: 33860199 Free PMC article.

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