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Evaluation of the antidepressant therapeutic potential of isocyanine and pseudoisocyanine analogues of the organic cation decynium-22.
Krause-Heuer AM, Fraser-Spears R, Dobrowolski JC, Ashford ME, Wyatt NA, Roberts MP, Gould GG, Cheah WC, Ng CKL, Bhadbhade M, Zhang B, Greguric I, Wheate NJ, Kumar N, Koek W, Callaghan PD, Daws LC, Fraser BH. Krause-Heuer AM, et al. Among authors: callaghan pd. Eur J Med Chem. 2017 Sep 8;137:476-487. doi: 10.1016/j.ejmech.2017.06.011. Epub 2017 Jun 7. Eur J Med Chem. 2017. PMID: 28624702 Free PMC article.
Comparative analysis of novel decynium-22 analogs to inhibit transport by the low-affinity, high-capacity monoamine transporters, organic cation transporters 2 and 3, and plasma membrane monoamine transporter.
Fraser-Spears R, Krause-Heuer AM, Basiouny M, Mayer FP, Manishimwe R, Wyatt NA, Dobrowolski JC, Roberts MP, Greguric I, Kumar N, Koek W, Sitte HH, Callaghan PD, Fraser BH, Daws LC. Fraser-Spears R, et al. Among authors: callaghan pd. Eur J Pharmacol. 2019 Jan 5;842:351-364. doi: 10.1016/j.ejphar.2018.10.028. Epub 2018 Oct 25. Eur J Pharmacol. 2019. PMID: 30473490 Free PMC article.
In vivo analysis of serotonin clearance in rat hippocampus reveals that repeated administration of p-methoxyamphetamine (PMA), but not 3,4-methylenedioxymethamphetamine (MDMA), leads to long-lasting deficits in serotonin transporter function.
Callaghan PD, Owens WA, Javors MA, Sanchez TA, Jones DJ, Irvine RJ, Daws LC. Callaghan PD, et al. J Neurochem. 2007 Feb;100(3):617-27. doi: 10.1111/j.1471-4159.2006.04247.x. Epub 2006 Dec 1. J Neurochem. 2007. PMID: 17181558 Free article.
Comparison of in vivo binding properties of the 18-kDa translocator protein (TSPO) ligands [(18)F]PBR102 and [ (18)F]PBR111 in a model of excitotoxin-induced neuroinflammation.
Callaghan PD, Wimberley CA, Rahardjo GL, Berghofer PJ, Pham TQ, Jackson T, Zahra D, Bourdier T, Wyatt N, Greguric I, Howell NR, Siegele R, Pastuovic Z, Mattner F, Loc'h C, Gregoire MC, Katsifis A. Callaghan PD, et al. Eur J Nucl Med Mol Imaging. 2015 Jan;42(1):138-51. doi: 10.1007/s00259-014-2895-3. Epub 2014 Sep 18. Eur J Nucl Med Mol Imaging. 2015. PMID: 25231248
33 results