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Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model.
Borgna V, Villegas J, Burzio VA, Belmar S, Araya M, Jeldes E, Lobos-González L, Silva V, Villota C, Oliveira-Cruz L, Lopez C, Socias T, Castillo O, Burzio LO. Borgna V, et al. Among authors: burzio lo. Oncotarget. 2017 Jul 4;8(27):43692-43708. doi: 10.18632/oncotarget.18460. Oncotarget. 2017. PMID: 28620146 Free PMC article.
Nuclear localization of the mitochondrial ncRNAs in normal and cancer cells.
Landerer E, Villegas J, Burzio VA, Oliveira L, Villota C, Lopez C, Restovic F, Martinez R, Castillo O, Burzio LO. Landerer E, et al. Among authors: burzio va, burzio lo. Cell Oncol (Dordr). 2011 Aug;34(4):297-305. doi: 10.1007/s13402-011-0018-8. Epub 2011 Feb 24. Cell Oncol (Dordr). 2011. PMID: 21347712
Down-regulation of the antisense mitochondrial non-coding RNAs (ncRNAs) is a unique vulnerability of cancer cells and a potential target for cancer therapy.
Vidaurre S, Fitzpatrick C, Burzio VA, Briones M, Villota C, Villegas J, Echenique J, Oliveira-Cruz L, Araya M, Borgna V, Socías T, Lopez C, Avila R, Burzio LO. Vidaurre S, et al. Among authors: burzio va, burzio lo. J Biol Chem. 2014 Sep 26;289(39):27182-27198. doi: 10.1074/jbc.M114.558841. Epub 2014 Aug 6. J Biol Chem. 2014. PMID: 25100722 Free PMC article.
Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factors.
Lobos-González L, Silva V, Araya M, Restovic F, Echenique J, Oliveira-Cruz L, Fitzpatrick C, Briones M, Villegas J, Villota C, Vidaurre S, Borgna V, Socias M, Valenzuela S, Lopez C, Socias T, Varas M, Díaz J, Burzio LO, Burzio VA. Lobos-González L, et al. Among authors: burzio lo. Oncotarget. 2016 Sep 6;7(36):58331-58350. doi: 10.18632/oncotarget.11110. Oncotarget. 2016. PMID: 27507060 Free PMC article.
Expression of mitochondrial non-coding RNAs (ncRNAs) is modulated by high risk human papillomavirus (HPV) oncogenes.
Villota C, Campos A, Vidaurre S, Oliveira-Cruz L, Boccardo E, Burzio VA, Varas M, Villegas J, Villa LL, Valenzuela PD, Socías M, Roberts S, Burzio LO. Villota C, et al. Among authors: burzio va, burzio lo. J Biol Chem. 2012 Jun 15;287(25):21303-15. doi: 10.1074/jbc.M111.326694. Epub 2012 Apr 26. J Biol Chem. 2012. PMID: 22539350 Free PMC article.
Mitochondrial ncRNA targeting induces cell cycle arrest and tumor growth inhibition of MDA-MB-231 breast cancer cells through reduction of key cell cycle progression factors.
Fitzpatrick C, Bendek MF, Briones M, Farfán N, Silva VA, Nardocci G, Montecino M, Boland A, Deleuze JF, Villegas J, Villota C, Silva V, Lobos-Gonzalez L, Borgna V, Barrey E, Burzio LO, Burzio VA. Fitzpatrick C, et al. Among authors: burzio lo. Cell Death Dis. 2019 May 29;10(6):423. doi: 10.1038/s41419-019-1649-3. Cell Death Dis. 2019. PMID: 31142736 Free PMC article.
64 results