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Cellular senescence drives age-dependent hepatic steatosis.
Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, Day CP, Burt A, Palmer A, Anstee QM, Grellscheid SN, Hoeijmakers JHJ, Barnhoorn S, Mann DA, Bird TG, Vermeij WP, Kirkland JL, Passos JF, von Zglinicki T, Jurk D. Ogrodnik M, et al. Among authors: mann da. Nat Commun. 2017 Jun 13;8:15691. doi: 10.1038/ncomms15691. Nat Commun. 2017. PMID: 28608850 Free PMC article.
Multigenerational epigenetic adaptation of the hepatic wound-healing response.
Zeybel M, Hardy T, Wong YK, Mathers JC, Fox CR, Gackowska A, Oakley F, Burt AD, Wilson CL, Anstee QM, Barter MJ, Masson S, Elsharkawy AM, Mann DA, Mann J. Zeybel M, et al. Among authors: mann da, mann j. Nat Med. 2012 Sep;18(9):1369-77. doi: 10.1038/nm.2893. Nat Med. 2012. PMID: 22941276 Free PMC article.
Tumor progression locus 2/Cot is required for activation of extracellular regulated kinase in liver injury and toll-like receptor-induced TIMP-1 gene transcription in hepatic stellate cells in mice.
Perugorria MJ, Murphy LB, Fullard N, Chakraborty JB, Vyrla D, Wilson CL, Oakley F, Mann J, Mann DA. Perugorria MJ, et al. Among authors: mann j, mann da. Hepatology. 2013 Mar;57(3):1238-49. doi: 10.1002/hep.26108. Hepatology. 2013. PMID: 23080298 Free article.
280 results