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RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates.
Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, Pollitt S, Baliga R, Murray CJ, Thanos CD, McEvoy LM, Sato AK, Hallam TJ. Yin G, et al. Among authors: stafford rl. Sci Rep. 2017 Jun 8;7(1):3026. doi: 10.1038/s41598-017-03192-z. Sci Rep. 2017. PMID: 28596531 Free PMC article.
In vitro Fab display: a cell-free system for IgG discovery.
Stafford RL, Matsumoto ML, Yin G, Cai Q, Fung JJ, Stephenson H, Gill A, You M, Lin SH, Wang WD, Masikat MR, Li X, Penta K, Steiner AR, Baliga R, Murray CJ, Thanos CD, Hallam TJ, Sato AK. Stafford RL, et al. Protein Eng Des Sel. 2014 Apr;27(4):97-109. doi: 10.1093/protein/gzu002. Epub 2014 Feb 28. Protein Eng Des Sel. 2014. PMID: 24586053 Free PMC article.
Targeting CD74 in multiple myeloma with the novel, site-specific antibody-drug conjugate STRO-001.
Abrahams CL, Li X, Embry M, Yu A, Krimm S, Krueger S, Greenland NY, Wen KW, Jones C, DeAlmeida V, Solis WA, Matheny S, Kline T, Yam AY, Stafford R, Wiita AP, Hallam T, Lupher M, Molina A. Abrahams CL, et al. Oncotarget. 2018 Dec 28;9(102):37700-37714. doi: 10.18632/oncotarget.26491. eCollection 2018 Dec 28. Oncotarget. 2018. PMID: 30701025 Free PMC article.
Minimization of a protein-DNA dimerizer.
Stafford RL, Arndt HD, Brezinski ML, Ansari AZ, Dervan PB. Stafford RL, et al. J Am Chem Soc. 2007 Mar 7;129(9):2660-8. doi: 10.1021/ja067971k. Epub 2007 Feb 10. J Am Chem Soc. 2007. PMID: 17290996 Free PMC article.
The reach of linear protein-DNA dimerizers.
Stafford RL, Dervan PB. Stafford RL, et al. J Am Chem Soc. 2007 Nov 14;129(45):14026-33. doi: 10.1021/ja075247b. Epub 2007 Oct 20. J Am Chem Soc. 2007. PMID: 17949089 Free PMC article.
25 results