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GCH1 plays a role in the high-altitude adaptation of Tibetans.
Guo YB, He YX, Cui CY, Ouzhu L, Baima K, Duoji Z, Deji Q, Bian B, Peng Y, Bai CJ, Gongga L, Pan YY, Qu L, Kang M, Ciren Y, Baima Y, Guo W, Yang L, Zhang H, Zhang XM, Zheng WS, Xu SH, Chen H, Zhao SG, Cai Y, Liu SM, Wu TY, Qi XB, Su B. Guo YB, et al. Among authors: zhang xm, zhang h. Zool Res. 2017 May 18;38(3):155-162. doi: 10.24272/j.issn.2095-8137.2017.037. Zool Res. 2017. PMID: 28585439 Free PMC article.
Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia.
Peng Y, Cui C, He Y, Ouzhuluobu, Zhang H, Yang D, Zhang Q, Bianbazhuoma, Yang L, He Y, Xiang K, Zhang X, Bhandari S, Shi P, Yangla, Dejiquzong, Baimakangzhuo, Duojizhuoma, Pan Y, Cirenyangji, Baimayangji, Gonggalanzi, Bai C, Bianba, Basang, Ciwangsangbu, Xu S, Chen H, Liu S, Wu T, Qi X, Su B. Peng Y, et al. Among authors: zhang q, zhang h, zhang x. Mol Biol Evol. 2017 Apr 1;34(4):818-830. doi: 10.1093/molbev/msw280. Mol Biol Evol. 2017. PMID: 28096303 Free PMC article.
EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production.
Zheng WS, He YX, Cui CY, Ouzhu L, Deji Q, Peng Y, Bai CJ, Duoji Z, Gongga L, Bian B, Baima K, Pan YY, Qu L, Kang M, Ciren Y, Baima Y, Guo W, Yang L, Zhang H, Zhang XM, Guo YB, Xu SH, Chen H, Zhao SG, Cai Y, Liu SM, Wu TY, Qi XB, Su B. Zheng WS, et al. Among authors: zhang xm, zhang h. Zool Res. 2017 May 18;38(3):163-170. doi: 10.24272/j.issn.2095-8137.2017.036. Zool Res. 2017. PMID: 28585440 Free PMC article.
Cross-altitude analysis suggests a turning point at the elevation of 4,500 m for polycythemia prevalence in Tibetans.
Zhang H, He Y, Cui C, Ouzhuluobu, Baimakangzhuo, Duojizhuoma, Dejiquzong, Bianba, Gonggalanzi, Pan Y, Qula, Kangmin, Cirenyangji, Baimayangji, Bai C, Guo W, Yangla, Peng Y, Zhang X, Xiang K, Yang Z, Liu S, Tao X, Gengdeng, Zheng W, Guo Y, Wu T, Qi X, Su B. Zhang H, et al. Among authors: zhang x. Am J Hematol. 2017 Sep;92(9):E552-E554. doi: 10.1002/ajh.24809. Epub 2017 Jul 19. Am J Hematol. 2017. PMID: 28589696 Free article. No abstract available.
Sherpas share genetic variations with Tibetans for high-altitude adaptation.
Bhandari S, Zhang X, Cui C, Yangla, Liu L, Ouzhuluobu, Baimakangzhuo, Gonggalanzi, Bai C, Bianba, Peng Y, Zhang H, Xiang K, Shi H, Liu S, Gengdeng, Wu T, Qi X, Su B. Bhandari S, et al. Among authors: zhang x, zhang h. Mol Genet Genomic Med. 2016 Nov 23;5(1):76-84. doi: 10.1002/mgg3.264. eCollection 2017 Jan. Mol Genet Genomic Med. 2016. PMID: 28116332 Free PMC article.
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