Wang Y - Search Results

1

Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response.

Li H, Yu J, Liu C, Liu J, Subramaniam S, Zhao H, Blumenthal GM, Turner DC, Li C, Ahamadi M, de Greef R, Chatterjee M, Kondic AG, Stone JA, Booth BP, Keegan P, Rahman A, Wang Y. Li H, et al. Among authors: wang y. J Pharmacokinet Pharmacodyn. 2017 Oct;44(5):403-414. doi: 10.1007/s10928-017-9528-y. Epub 2017 Jun 1. J Pharmacokinet Pharmacodyn. 2017. PMID: 28573468

2

Impact of pharmacometrics on drug approval and labeling decisions: a survey of 42 new drug applications.

Bhattaram VA, Booth BP, Ramchandani RP, Beasley BN, Wang Y, Tandon V, Duan JZ, Baweja RK, Marroum PJ, Uppoor RS, Rahman NA, Sahajwalla CG, Powell JR, Mehta MU, Gobburu JV. Bhattaram VA, et al. Among authors: wang y. AAPS J. 2005 Oct 7;7(3):E503-12. doi: 10.1208/aapsj070351. AAPS J. 2005. PMID: 16353928 Free PMC article. Review.

3

The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity.

Ramchandani RP, Wang Y, Booth BP, Ibrahim A, Johnson JR, Rahman A, Mehta M, Innocenti F, Ratain MJ, Gobburu JV. Ramchandani RP, et al. Among authors: wang y. J Clin Pharmacol. 2007 Jan;47(1):78-86. doi: 10.1177/0091270006295060. J Clin Pharmacol. 2007. PMID: 17192505

4

Derivation of various NONMEM estimation methods.

Wang Y. Wang Y. J Pharmacokinet Pharmacodyn. 2007 Oct;34(5):575-93. doi: 10.1007/s10928-007-9060-6. Epub 2007 Jul 10. J Pharmacokinet Pharmacodyn. 2007. PMID: 17620001

5

Elucidation of relationship between tumor size and survival in non-small-cell lung cancer patients can aid early decision making in clinical drug development.

Wang Y, Sung C, Dartois C, Ramchandani R, Booth BP, Rock E, Gobburu J. Wang Y, et al. Clin Pharmacol Ther. 2009 Aug;86(2):167-74. doi: 10.1038/clpt.2009.64. Epub 2009 May 13. Clin Pharmacol Ther. 2009. PMID: 19440187

6

Impact of pharmacometric analyses on new drug approval and labelling decisions: a review of 198 submissions between 2000 and 2008.

Lee JY, Garnett CE, Gobburu JV, Bhattaram VA, Brar S, Earp JC, Jadhav PR, Krudys K, Lesko LJ, Li F, Liu J, Madabushi R, Marathe A, Mehrotra N, Tornoe C, Wang Y, Zhu H. Lee JY, et al. Among authors: wang y. Clin Pharmacokinet. 2011 Oct;50(10):627-35. doi: 10.2165/11593210-000000000-00000. Clin Pharmacokinet. 2011. PMID: 21895036

7

Evaluation of false positive rate based on exposure-response analyses for two compounds in fixed-dose combination products.

Zhu H, Wang Y. Zhu H, et al. Among authors: wang y. J Pharmacokinet Pharmacodyn. 2011 Dec;38(6):671-96. doi: 10.1007/s10928-011-9214-4. Epub 2011 Sep 6. J Pharmacokinet Pharmacodyn. 2011. PMID: 21898140

8

Improper selection of a pre-specified primary dose-response analysis delays regulatory drug approval.

Liu J, Jadhav P, Wang Y, Gobburu J. Liu J, et al. Among authors: wang y. AAPS J. 2013 Apr;15(2):407-14. doi: 10.1208/s12248-012-9438-2. Epub 2013 Jan 10. AAPS J. 2013. PMID: 23307587 Free PMC article.

9

The combination of exposure-response and case-control analyses in regulatory decision making.

Yang J, Zhao H, Garnett C, Rahman A, Gobburu JV, Pierce W, Schechter G, Summers J, Keegan P, Booth B, Wang Y. Yang J, et al. Among authors: wang y. J Clin Pharmacol. 2013 Feb;53(2):160-6. doi: 10.1177/0091270012445206. Epub 2013 Jan 24. J Clin Pharmacol. 2013. PMID: 23436261 Clinical Trial.

10

Development of a placebo effect model combined with a dropout model for bipolar disorder.

Sun W, Laughren TP, Zhu H, Hochhaus G, Wang Y. Sun W, et al. Among authors: wang y. J Pharmacokinet Pharmacodyn. 2013 Jun;40(3):359-68. doi: 10.1007/s10928-013-9305-5. Epub 2013 Mar 2. J Pharmacokinet Pharmacodyn. 2013. PMID: 23456101

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