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Rifamycin action on RNA polymerase in antibiotic-tolerant Mycobacterium tuberculosis results in differentially detectable populations.
Saito K, Warrier T, Somersan-Karakaya S, Kaminski L, Mi J, Jiang X, Park S, Shigyo K, Gold B, Roberts J, Weber E, Jacobs WR Jr, Nathan CF. Saito K, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4832-E4840. doi: 10.1073/pnas.1705385114. Epub 2017 May 30. Proc Natl Acad Sci U S A. 2017. PMID: 28559332 Free PMC article.
Selective killing of nonreplicating mycobacteria.
Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S, Cherian J, Rhee K, Ly L, Converse PJ, Ehrt S, Vandal O, Jiang X, Schneider J, Lin G, Nathan C. Bryk R, et al. Among authors: jiang x. Cell Host Microbe. 2008 Mar 13;3(3):137-45. doi: 10.1016/j.chom.2008.02.003. Cell Host Microbe. 2008. PMID: 18329613 Free PMC article.
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Gold B, Pingle M, Brickner SJ, Shah N, Roberts J, Rundell M, Bracken WC, Warrier T, Somersan S, Venugopal A, Darby C, Jiang X, Warren JD, Fernandez J, Ouerfelli O, Nuermberger EL, Cunningham-Bussel A, Rath P, Chidawanyika T, Deng H, Realubit R, Glickman JF, Nathan CF. Gold B, et al. Among authors: jiang x. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16004-11. doi: 10.1073/pnas.1214188109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23012453 Free PMC article.
Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.
Darby CM, Ingólfsson HI, Jiang X, Shen C, Sun M, Zhao N, Burns K, Liu G, Ehrt S, Warren JD, Andersen OS, Brickner SJ, Nathan C. Darby CM, et al. Among authors: jiang x. PLoS One. 2013 Jul 30;8(7):e68942. doi: 10.1371/journal.pone.0068942. Print 2013. PLoS One. 2013. PMID: 23935911 Free PMC article.
Benzimidazole-based compounds kill Mycobacterium tuberculosis.
Gong Y, Somersan Karakaya S, Guo X, Zheng P, Gold B, Ma Y, Little D, Roberts J, Warrier T, Jiang X, Pingle M, Nathan CF, Liu G. Gong Y, et al. Among authors: jiang x. Eur J Med Chem. 2014 Mar 21;75:336-53. doi: 10.1016/j.ejmech.2014.01.039. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24556148
Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis.
Zhao N, Darby CM, Small J, Bachovchin DA, Jiang X, Burns-Huang KE, Botella H, Ehrt S, Boger DL, Anderson ED, Cravatt BF, Speers AE, Fernandez-Vega V, Hodder PS, Eberhart C, Rosen H, Spicer TP, Nathan CF. Zhao N, et al. Among authors: jiang x. ACS Chem Biol. 2015 Feb 20;10(2):364-71. doi: 10.1021/cb500746z. Epub 2014 Dec 5. ACS Chem Biol. 2015. PMID: 25457457 Free PMC article.
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