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The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.
Goodwin J, Neugent ML, Lee SY, Choe JH, Choi H, Jenkins DMR, Ruthenborg RJ, Robinson MW, Jeong JY, Wake M, Abe H, Takeda N, Endo H, Inoue M, Xuan Z, Yoo H, Chen M, Ahn JM, Minna JD, Helke KL, Singh PK, Shackelford DB, Kim JW. Goodwin J, et al. Among authors: takeda n. Nat Commun. 2017 May 26;8:15503. doi: 10.1038/ncomms15503. Nat Commun. 2017. PMID: 28548087 Free PMC article.
Sinus of Valsalva aneurysm accompanying bicuspid aortic valve.
Abe H, Takeda N, Aoki H, Nagai R. Abe H, et al. Among authors: takeda n. Intern Med. 2012;51(10):1275. doi: 10.2169/internalmedicine.51.7477. Epub 2012 May 15. Intern Med. 2012. PMID: 22687805 Free article. No abstract available.
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity.
Semba H, Takeda N, Isagawa T, Sugiura Y, Honda K, Wake M, Miyazawa H, Yamaguchi Y, Miura M, Jenkins DM, Choi H, Kim JW, Asagiri M, Cowburn AS, Abe H, Soma K, Koyama K, Katoh M, Sayama K, Goda N, Johnson RS, Manabe I, Nagai R, Komuro I. Semba H, et al. Among authors: takeda n. Nat Commun. 2016 May 18;7:11635. doi: 10.1038/ncomms11635. Nat Commun. 2016. PMID: 27189088 Free PMC article.
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis.
Goodwin J, Choi H, Hsieh MH, Neugent ML, Ahn JM, Hayenga HN, Singh PK, Shackelford DB, Lee IK, Shulaev V, Dhar S, Takeda N, Kim JW. Goodwin J, et al. Among authors: takeda n. Am J Respir Cell Mol Biol. 2018 Feb;58(2):216-231. doi: 10.1165/rcmb.2016-0186OC. Am J Respir Cell Mol Biol. 2018. PMID: 28915065 Free PMC article.
2,063 results