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Molecular insights into melanoma brain metastases.
Westphal D, Glitza Oliva IC, Niessner H. Westphal D, et al. Among authors: niessner h. Cancer. 2017 Jun 1;123(S11):2163-2175. doi: 10.1002/cncr.30594. Cancer. 2017. PMID: 28543697 Free article. Review.
Targeting hyperactivation of the AKT survival pathway to overcome therapy resistance of melanoma brain metastases.
Niessner H, Forschner A, Klumpp B, Honegger JB, Witte M, Bornemann A, Dummer R, Adam A, Bauer J, Tabatabai G, Flaherty K, Sinnberg T, Beck D, Leiter U, Mauch C, Roesch A, Weide B, Eigentler T, Schadendorf D, Garbe C, Kulms D, Quintanilla-Martinez L, Meier F. Niessner H, et al. Cancer Med. 2013 Feb;2(1):76-85. doi: 10.1002/cam4.50. Epub 2013 Feb 3. Cancer Med. 2013. PMID: 24133630 Free PMC article.
PI3K Pathway Inhibition Achieves Potent Antitumor Activity in Melanoma Brain Metastases In Vitro and In Vivo.
Niessner H, Schmitz J, Tabatabai G, Schmid AM, Calaminus C, Sinnberg T, Weide B, Eigentler TK, Garbe C, Schittek B, Quintanilla-Fend L, Bender B, Mai M, Praetorius C, Beissert S, Schackert G, Muders MH, Meinhardt M, Baretton GB, Dummer R, Flaherty K, Pichler BJ, Kulms D, Westphal D, Meier F. Niessner H, et al. Clin Cancer Res. 2016 Dec 1;22(23):5818-5828. doi: 10.1158/1078-0432.CCR-16-0064. Epub 2016 Jun 15. Clin Cancer Res. 2016. PMID: 27307593 Free article.
An open-label, single-arm, phase II trial of buparlisib in patients with melanoma brain metastases not eligible for surgery or radiosurgery-the BUMPER study.
Amaral T, Niessner H, Sinnberg T, Thomas I, Meiwes A, Garbe C, Garzarolli M, Rauschenberg R, Eigentler T, Meier F. Amaral T, et al. Among authors: niessner h. Neurooncol Adv. 2020 Oct 22;2(1):vdaa140. doi: 10.1093/noajnl/vdaa140. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 33305271 Free PMC article.
Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy.
Bochem J, Zelba H, Spreuer J, Amaral T, Wagner NB, Gaissler A, Pop OT, Thiel K, Yurttas C, Soffel D, Forchhammer S, Sinnberg T, Niessner H, Meier F, Terheyden P, Königsrainer A, Garbe C, Flatz L, Pawelec G, Eigentler TK, Löffler MW, Weide B, Wistuba-Hamprecht K. Bochem J, et al. Among authors: niessner h. J Immunother Cancer. 2021 Dec;9(12):e003439. doi: 10.1136/jitc-2021-003439. J Immunother Cancer. 2021. PMID: 34933966 Free PMC article.
Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases.
Chatziioannou E, Roßner J, Aung TN, Rimm DL, Niessner H, Keim U, Serna-Higuita LM, Bonzheim I, Kuhn Cuellar L, Westphal D, Steininger J, Meier F, Pop OT, Forchhammer S, Flatz L, Eigentler T, Garbe C, Röcken M, Amaral T, Sinnberg T. Chatziioannou E, et al. Among authors: niessner h. EBioMedicine. 2023 Jul;93:104644. doi: 10.1016/j.ebiom.2023.104644. Epub 2023 Jun 7. EBioMedicine. 2023. PMID: 37295047 Free PMC article.
145 results