Guarente L - Search Results

1

SIRT1 is a positive regulator of the master osteoblast transcription factor, RUNX2.

Zainabadi K, Liu CJ, Guarente L. Zainabadi K, et al. Among authors: guarente l. PLoS One. 2017 May 25;12(5):e0178520. doi: 10.1371/journal.pone.0178520. eCollection 2017. PLoS One. 2017. PMID: 28542607 Free PMC article.

2

SIRT1 is a positive regulator of in vivo bone mass and a therapeutic target for osteoporosis.

Zainabadi K, Liu CJ, Caldwell ALM, Guarente L. Zainabadi K, et al. Among authors: guarente l. PLoS One. 2017 Sep 22;12(9):e0185236. doi: 10.1371/journal.pone.0185236. eCollection 2017. PLoS One. 2017. PMID: 28937996 Free PMC article.

3

SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin.

Simic P, Zainabadi K, Bell E, Sykes DB, Saez B, Lotinun S, Baron R, Scadden D, Schipani E, Guarente L. Simic P, et al. Among authors: guarente l. EMBO Mol Med. 2013 Mar;5(3):430-40. doi: 10.1002/emmm.201201606. Epub 2013 Jan 30. EMBO Mol Med. 2013. PMID: 23364955 Free PMC article.

4

Myeloid cell sirtuin-1 expression does not alter host immune responses to Gram-negative endotoxemia or Gram-positive bacterial infection.

Crotty Alexander LE, Marsh BJ, Timmer AM, Lin AE, Zainabadi K, Czopik A, Guarente L, Nizet V. Crotty Alexander LE, et al. Among authors: guarente l. PLoS One. 2013 Dec 26;8(12):e84481. doi: 10.1371/journal.pone.0084481. eCollection 2013. PLoS One. 2013. PMID: 24386389 Free PMC article.

5

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

Firestein R, Blander G, Michan S, Oberdoerffer P, Ogino S, Campbell J, Bhimavarapu A, Luikenhuis S, de Cabo R, Fuchs C, Hahn WC, Guarente LP, Sinclair DA. Firestein R, et al. PLoS One. 2008 Apr 16;3(4):e2020. doi: 10.1371/journal.pone.0002020. PLoS One. 2008. PMID: 18414679 Free PMC article.

6

SIRT1 protects against α-synuclein aggregation by activating molecular chaperones.

Donmez G, Arun A, Chung CY, McLean PJ, Lindquist S, Guarente L. Donmez G, et al. Among authors: guarente l. J Neurosci. 2012 Jan 4;32(1):124-32. doi: 10.1523/JNEUROSCI.3442-11.2012. J Neurosci. 2012. PMID: 22219275 Free PMC article. Retracted.

7

Sirt3 deficiency does not affect venous thrombosis or NETosis despite mild elevation of intracellular ROS in platelets and neutrophils in mice.

Hayashi H, Cherpokova D, Martinod K, Witsch T, Wong SL, Gallant M, Cifuni SM, Guarente LP, Wagner DD. Hayashi H, et al. PLoS One. 2017 Dec 13;12(12):e0188341. doi: 10.1371/journal.pone.0188341. eCollection 2017. PLoS One. 2017. PMID: 29236713 Free PMC article.

8

SirT1 is required in the male germ cell for differentiation and fecundity in mice.

Bell EL, Nagamori I, Williams EO, Del Rosario AM, Bryson BD, Watson N, White FM, Sassone-Corsi P, Guarente L. Bell EL, et al. Among authors: guarente l. Development. 2014 Sep;141(18):3495-504. doi: 10.1242/dev.110627. Epub 2014 Aug 19. Development. 2014. PMID: 25142464 Free PMC article.

9

Neurogenesis directed by Sirt1.

Libert S, Cohen D, Guarente L. Libert S, et al. Among authors: guarente l. Nat Cell Biol. 2008 Apr;10(4):373-4. doi: 10.1038/ncb0408-373. Nat Cell Biol. 2008. PMID: 18379594 Free PMC article.

10

SIRT1 and other sirtuins in metabolism.

Chang HC, Guarente L. Chang HC, et al. Among authors: guarente l. Trends Endocrinol Metab. 2014 Mar;25(3):138-45. doi: 10.1016/j.tem.2013.12.001. Epub 2013 Dec 30. Trends Endocrinol Metab. 2014. PMID: 24388149 Free PMC article. Review.

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