Chen ZJ - Search Results

1

cGAS is essential for cellular senescence.

Yang H, Wang H, Ren J, Chen Q, Chen ZJ. Yang H, et al. Among authors: chen zj, chen q. Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):E4612-E4620. doi: 10.1073/pnas.1705499114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533362 Free PMC article.

2

Essential role of TAK1 in thymocyte development and activation.

Liu HH, Xie M, Schneider MD, Chen ZJ. Liu HH, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82. doi: 10.1073/pnas.0603089103. Epub 2006 Jul 20. Proc Natl Acad Sci U S A. 2006. PMID: 16857737 Free PMC article.

3

MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus.

Bhoj VG, Sun Q, Bhoj EJ, Somers C, Chen X, Torres JP, Mejias A, Gomez AM, Jafri H, Ramilo O, Chen ZJ. Bhoj VG, et al. Among authors: chen zj, chen x. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):14046-51. doi: 10.1073/pnas.0804717105. Epub 2008 Sep 9. Proc Natl Acad Sci U S A. 2008. PMID: 18780793 Free PMC article.

4

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis.

Li XD, Chiu YH, Ismail AS, Behrendt CL, Wight-Carter M, Hooper LV, Chen ZJ. Li XD, et al. Among authors: chen zj. Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17390-5. doi: 10.1073/pnas.1107114108. Epub 2011 Sep 29. Proc Natl Acad Sci U S A. 2011. PMID: 21960441 Free PMC article.

5

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.

Sun L, Wu J, Du F, Chen X, Chen ZJ. Sun L, et al. Among authors: chen zj, chen x. Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012 Dec 20. Science. 2013. PMID: 23258413 Free PMC article.

6

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses.

Gao D, Wu J, Wu YT, Du F, Aroh C, Yan N, Sun L, Chen ZJ. Gao D, et al. Among authors: chen zj. Science. 2013 Aug 23;341(6148):903-6. doi: 10.1126/science.1240933. Epub 2013 Aug 8. Science. 2013. PMID: 23929945 Free PMC article.

7

Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects.

Li XD, Wu J, Gao D, Wang H, Sun L, Chen ZJ. Li XD, et al. Among authors: chen zj. Science. 2013 Sep 20;341(6152):1390-4. doi: 10.1126/science.1244040. Epub 2013 Aug 29. Science. 2013. PMID: 23989956 Free PMC article.

8

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.

Zhang X, Wu J, Du F, Xu H, Sun L, Chen Z, Brautigam CA, Zhang X, Chen ZJ. Zhang X, et al. Among authors: chen z, chen zj. Cell Rep. 2014 Feb 13;6(3):421-30. doi: 10.1016/j.celrep.2014.01.003. Epub 2014 Jan 23. Cell Rep. 2014. PMID: 24462292 Free PMC article.

9

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.

Cai X, Chiu YH, Chen ZJ. Cai X, et al. Among authors: chen zj. Mol Cell. 2014 Apr 24;54(2):289-96. doi: 10.1016/j.molcel.2014.03.040. Mol Cell. 2014. PMID: 24766893 Free article. Review.

10

IKKβ is an IRF5 kinase that instigates inflammation.

Ren J, Chen X, Chen ZJ. Ren J, et al. Among authors: chen zj, chen x. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17438-43. doi: 10.1073/pnas.1418516111. Epub 2014 Oct 17. Proc Natl Acad Sci U S A. 2014. PMID: 25326420 Free PMC article.

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